MotifHXC4.H12CORE.0.SM.B
Gene (human)HOXC4
(GeneCards)
Gene synonyms (human)HOX3E
Gene (mouse)Hoxc4
Gene synonyms (mouse)Hox-3.5, Hoxc-4
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length13
ConsensusnbvYTAATKAbbn
GC content36.04%
Information content (bits; total / per base)11.786 / 0.907
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9636

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.982 0.969 0.957 0.94 0.849 0.85
best 0.983 0.97 0.97 0.953 0.931 0.911
Methyl HT-SELEX, 1 experiments median 0.981 0.969 0.944 0.926 0.766 0.79
best 0.981 0.969 0.944 0.926 0.766 0.79
Non-Methyl HT-SELEX, 1 experiments median 0.983 0.97 0.97 0.953 0.931 0.911
best 0.983 0.97 0.97 0.953 0.931 0.911
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX4 {3.1.1.4} (TFClass)
TFClass IDTFClass: 3.1.1.4.3
HGNCHGNC:5126
MGIMGI:96195
EntrezGene (human)GeneID:3221
(SSTAR profile)
EntrezGene (mouse)GeneID:15423
(SSTAR profile)
UniProt ID (human)HXC4_HUMAN
UniProt ID (mouse)HXC4_MOUSE
UniProt AC (human)P09017
(TFClass)
UniProt AC (mouse)Q08624
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
013225.252076.252113.252221.25
021717.254318.251786.251814.25
032434.02516.04328.0358.0
04401.03988.0276.04971.0
050.00.00.09636.0
069636.00.00.00.0
079636.00.00.00.0
080.0220.00.09416.0
093.06.05098.04529.0
108584.010.01039.03.0
11597.04375.01748.02916.0
121489.753734.752568.751842.75
132271.52742.52198.52423.5
PFM
ACGT
010.3350.2150.2190.231
020.1780.4480.1850.188
030.2530.2610.4490.037
040.0420.4140.0290.516
050.00.00.01.0
061.00.00.00.0
071.00.00.00.0
080.00.0230.00.977
090.00.0010.5290.47
100.8910.0010.1080.0
110.0620.4540.1810.303
120.1550.3880.2670.191
130.2360.2850.2280.252
PWM
ACGT
010.292-0.148-0.131-0.081
02-0.3380.583-0.299-0.283
030.010.0430.585-1.901
04-1.7880.504-2.1590.724
05-6.958-6.958-6.9581.386
061.386-6.958-6.958-6.958
071.386-6.958-6.958-6.958
08-6.958-2.384-6.9581.362
09-6.121-5.6720.7490.631
101.27-5.279-0.84-6.121
11-1.3920.596-0.320.191
12-0.480.4380.064-0.268
13-0.0590.13-0.0910.006
Standard thresholds
P-value Threshold
0.001 3.11931
0.0005 5.18676
0.0001 7.88546