MotifHXC12.H12CORE.0.SM.B
Gene (human)HOXC12
(GeneCards)
Gene synonyms (human)HOC3F, HOX3F
Gene (mouse)Hoxc12
Gene synonyms (mouse)Hox-3.8, Hoxc-12
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length11
ConsensusnKTTTACGASn
GC content35.94%
Information content (bits; total / per base)12.839 / 1.167
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words1598

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.937 0.919 0.832 0.815 0.701 0.709
best 0.996 0.994 0.989 0.985 0.933 0.926
Methyl HT-SELEX, 1 experiments median 0.971 0.961 0.874 0.86 0.737 0.744
best 0.971 0.961 0.874 0.86 0.737 0.744
Non-Methyl HT-SELEX, 3 experiments median 0.902 0.878 0.79 0.769 0.665 0.673
best 0.996 0.994 0.989 0.985 0.933 0.926
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX9-13 {3.1.1.8} (TFClass)
TFClass IDTFClass: 3.1.1.8.12
HGNCHGNC:5124
MGIMGI:96194
EntrezGene (human)GeneID:3228
(SSTAR profile)
EntrezGene (mouse)GeneID:15421
(SSTAR profile)
UniProt ID (human)HXC12_HUMAN
UniProt ID (mouse)HXC12_MOUSE
UniProt AC (human)P31275
(TFClass)
UniProt AC (mouse)Q8K5B8
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01375.5354.5402.5465.5
02177.5148.5270.51001.5
0367.04.011.01516.0
044.00.00.01594.0
05103.00.00.01495.0
061598.00.00.00.0
070.01321.00.0277.0
082.034.01487.075.0
091502.07.086.03.0
1015.5804.5409.5368.5
11206.5567.5410.5413.5
PFM
ACGT
010.2350.2220.2520.291
020.1110.0930.1690.627
030.0420.0030.0070.949
040.0030.00.00.997
050.0640.00.00.936
061.00.00.00.0
070.00.8270.00.173
080.0010.0210.9310.047
090.940.0040.0540.002
100.010.5030.2560.231
110.1290.3550.2570.259
PWM
ACGT
01-0.062-0.1190.0070.152
02-0.806-0.982-0.3880.916
03-1.763-4.229-3.4421.33
04-4.229-5.383-5.3831.38
05-1.342-5.383-5.3831.316
061.383-5.383-5.383-5.383
07-5.3831.193-5.383-0.364
08-4.648-2.4161.311-1.653
091.321-3.815-1.519-4.417
10-3.1420.6980.025-0.08
11-0.6560.350.0270.034
Standard thresholds
P-value Threshold
0.001 3.337075
0.0005 4.594105
0.0001 7.279325