MotifHXC11.H12INVIVO.1.S.D
Gene (human)HOXC11
(GeneCards)
Gene synonyms (human)HOX3H
Gene (mouse)Hoxc11
Gene synonyms (mouse)Hox-3.7, Hoxc-11
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
D
Motif length10
ConsensushWTWAYGRbn
GC content32.43%
Information content (bits; total / per base)8.113 / 0.811
Data sourcesHT-SELEX
Aligned words8809

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 10 experiments median 0.973 0.949 0.958 0.935 0.873 0.857
best 0.984 0.966 0.986 0.97 0.969 0.954
Methyl HT-SELEX, 3 experiments median 0.976 0.956 0.971 0.95 0.945 0.922
best 0.984 0.962 0.986 0.97 0.969 0.954
Non-Methyl HT-SELEX, 7 experiments median 0.854 0.797 0.764 0.722 0.672 0.654
best 0.981 0.966 0.979 0.96 0.952 0.934
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX9-13 {3.1.1.8} (TFClass)
TFClass IDTFClass: 3.1.1.8.10
HGNCHGNC:5123
MGIMGI:96193
EntrezGene (human)GeneID:3227
(SSTAR profile)
EntrezGene (mouse)GeneID:109663
(SSTAR profile)
UniProt ID (human)HXC11_HUMAN
UniProt ID (mouse)HXC11_MOUSE
UniProt AC (human)O43248
(TFClass)
UniProt AC (mouse)P31313
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 7
Methyl-HT-SELEX 3
PCM
ACGT
011893.751683.751670.753560.75
02872.5404.5713.56818.5
03194.032.0180.08403.0
044513.00.029.04267.0
058778.00.031.00.0
06325.03278.00.05206.0
0796.0441.07161.01111.0
085090.0555.02014.01150.0
09648.752754.752908.752496.75
101586.752347.752358.752515.75
PFM
ACGT
010.2150.1910.190.404
020.0990.0460.0810.774
030.0220.0040.020.954
040.5120.00.0030.484
050.9960.00.0040.0
060.0370.3720.00.591
070.0110.050.8130.126
080.5780.0630.2290.131
090.0740.3130.330.283
100.180.2670.2680.286
PWM
ACGT
01-0.151-0.268-0.2760.48
02-0.924-1.69-1.1251.129
03-2.419-4.164-2.4931.338
040.717-6.878-4.2560.661
051.382-6.878-4.194-6.878
06-1.9070.397-6.8780.86
07-3.111-1.6041.178-0.683
080.837-1.375-0.089-0.649
09-1.220.2240.2780.125
10-0.3270.0640.0690.133
Standard thresholds
P-value Threshold
0.001 5.26852
0.0005 5.962105
0.0001 7.298645