HXC11.H12INVITRO.1.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	HXC11.H12INVITRO.1.S.B
Gene (human)	HOXC11 (GeneCards)
Gene synonyms (human)	HOX3H
Gene (mouse)	Hoxc11
Gene synonyms (mouse)	Hox-3.7, Hoxc-11
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	10
Consensus	hWTWAYGRbn
GC content	32.43%
Information content (bits; total / per base)	8.113 / 0.811
Data sources	HT-SELEX
Aligned words	8809

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 10 experiments	median	0.973	0.949	0.958	0.935	0.873	0.857
Overall, 10 experiments	best	0.984	0.966	0.986	0.97	0.969	0.954
Methyl HT-SELEX, 3 experiments	median	0.976	0.956	0.971	0.95	0.945	0.922
Methyl HT-SELEX, 3 experiments	best	0.984	0.962	0.986	0.97	0.969	0.954
Non-Methyl HT-SELEX, 7 experiments	median	0.854	0.797	0.764	0.722	0.672	0.654
Non-Methyl HT-SELEX, 7 experiments	best	0.981	0.966	0.979	0.96	0.952	0.934

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	HOX-related {3.1.1} (TFClass)
TF subfamily	HOX9-13 {3.1.1.8} (TFClass)
TFClass ID	TFClass: 3.1.1.8.10
HGNC	HGNC:5123
MGI	MGI:96193
EntrezGene (human)	GeneID:3227 (SSTAR profile)
EntrezGene (mouse)	GeneID:109663 (SSTAR profile)
UniProt ID (human)	HXC11_HUMAN
UniProt ID (mouse)	HXC11_MOUSE
UniProt AC (human)	O43248 (TFClass)
UniProt AC (mouse)	P31313 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	7
Methyl-HT-SELEX	3

PCM	HXC11.H12INVITRO.1.S.B.pcm
PWM	HXC11.H12INVITRO.1.S.B.pwm
PFM	HXC11.H12INVITRO.1.S.B.pfm
Alignment	HXC11.H12INVITRO.1.S.B.words.tsv
Threshold to P-value map	HXC11.H12INVITRO.1.S.B.thr
Motif in other formats
JASPAR format	HXC11.H12INVITRO.1.S.B_jaspar_format.txt
MEME format	HXC11.H12INVITRO.1.S.B_meme_format.meme
Transfac format	HXC11.H12INVITRO.1.S.B_transfac_format.txt
Homer format	HXC11.H12INVITRO.1.S.B_homer_format_0.001.txt HXC11.H12INVITRO.1.S.B_homer_format_0.0005.txt HXC11.H12INVITRO.1.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1893.75	1683.75	1670.75	3560.75
02	872.5	404.5	713.5	6818.5
03	194.0	32.0	180.0	8403.0
04	4513.0	0.0	29.0	4267.0
05	8778.0	0.0	31.0	0.0
06	325.0	3278.0	0.0	5206.0
07	96.0	441.0	7161.0	1111.0
08	5090.0	555.0	2014.0	1150.0
09	648.75	2754.75	2908.75	2496.75
10	1586.75	2347.75	2358.75	2515.75

PFM

	A	C	G	T
01	0.215	0.191	0.19	0.404
02	0.099	0.046	0.081	0.774
03	0.022	0.004	0.02	0.954
04	0.512	0.0	0.003	0.484
05	0.996	0.0	0.004	0.0
06	0.037	0.372	0.0	0.591
07	0.011	0.05	0.813	0.126
08	0.578	0.063	0.229	0.131
09	0.074	0.313	0.33	0.283
10	0.18	0.267	0.268	0.286

PWM

	A	C	G	T
01	-0.151	-0.268	-0.276	0.48
02	-0.924	-1.69	-1.125	1.129
03	-2.419	-4.164	-2.493	1.338
04	0.717	-6.878	-4.256	0.661
05	1.382	-6.878	-4.194	-6.878
06	-1.907	0.397	-6.878	0.86
07	-3.111	-1.604	1.178	-0.683
08	0.837	-1.375	-0.089	-0.649
09	-1.22	0.224	0.278	0.125
10	-0.327	0.064	0.069	0.133

Standard thresholds

P-value	Threshold
0.001	5.26852
0.0005	5.962105
0.0001	7.298645