MotifHXC11.H12INVITRO.0.SM.B
Gene (human)HOXC11
(GeneCards)
Gene synonyms (human)HOX3H
Gene (mouse)Hoxc11
Gene synonyms (mouse)Hox-3.7, Hoxc-11
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length11
ConsensusnTTTACGAYbn
GC content38.72%
Information content (bits; total / per base)11.932 / 1.085
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9377

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 10 experiments median 0.991 0.985 0.961 0.951 0.864 0.856
best 0.999 0.999 0.999 0.998 0.982 0.98
Methyl HT-SELEX, 3 experiments median 0.996 0.993 0.988 0.983 0.947 0.938
best 0.999 0.999 0.999 0.998 0.982 0.98
Non-Methyl HT-SELEX, 7 experiments median 0.82 0.789 0.725 0.698 0.645 0.634
best 0.998 0.997 0.995 0.993 0.946 0.943
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX9-13 {3.1.1.8} (TFClass)
TFClass IDTFClass: 3.1.1.8.10
HGNCHGNC:5123
MGIMGI:96193
EntrezGene (human)GeneID:3227
(SSTAR profile)
EntrezGene (mouse)GeneID:109663
(SSTAR profile)
UniProt ID (human)HXC11_HUMAN
UniProt ID (mouse)HXC11_MOUSE
UniProt AC (human)O43248
(TFClass)
UniProt AC (mouse)P31313
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 7
Methyl-HT-SELEX 3
PCM
ACGT
012032.51811.51883.53649.5
02722.5257.5730.57666.5
03104.058.029.09186.0
042910.015.01.06451.0
059376.00.01.00.0
060.08496.00.0881.0
0710.012.09287.068.0
088889.0105.0204.0179.0
0953.05637.0981.02706.0
101520.53785.52493.51577.5
111952.52499.51652.53272.5
PFM
ACGT
010.2170.1930.2010.389
020.0770.0270.0780.818
030.0110.0060.0030.98
040.310.0020.00.688
051.00.00.00.0
060.00.9060.00.094
070.0010.0010.990.007
080.9480.0110.0220.019
090.0060.6010.1050.289
100.1620.4040.2660.168
110.2080.2670.1760.349
PWM
ACGT
01-0.143-0.258-0.2190.442
02-1.175-2.201-1.1641.184
03-3.095-3.662-4.3181.365
040.216-4.911-6.5711.012
051.385-6.934-6.571-6.934
06-6.9341.287-6.934-0.977
07-5.252-5.1011.376-3.508
081.332-3.085-2.431-2.561
09-3.7480.877-0.870.143
10-0.4320.4790.062-0.396
11-0.1830.064-0.3490.333
Standard thresholds
P-value Threshold
0.001 3.74866
0.0005 5.05085
0.0001 7.44843