MotifHXC10.H12INVITRO.1.S.B
Gene (human)HOXC10
(GeneCards)
Gene synonyms (human)HOX3I
Gene (mouse)Hoxc10
Gene synonyms (mouse)Hox-3.6, Hoxc-10
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length12
ConsensusnhTTTATGRbbn
GC content35.33%
Information content (bits; total / per base)11.95 / 0.996
Data sourcesHT-SELEX
Aligned words6288

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 2 (10) 0.634 0.682 0.472 0.513 0.622 0.676 1.546 1.777 13.054 29.796

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.951 0.92 0.922 0.886 0.852 0.822
best 0.98 0.962 0.977 0.959 0.969 0.949
Methyl HT-SELEX, 2 experiments median 0.976 0.955 0.972 0.95 0.958 0.935
best 0.98 0.962 0.977 0.959 0.969 0.949
Non-Methyl HT-SELEX, 6 experiments median 0.919 0.88 0.87 0.827 0.778 0.752
best 0.974 0.954 0.967 0.944 0.949 0.923
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX9-13 {3.1.1.8} (TFClass)
TFClass IDTFClass: 3.1.1.8.7
HGNCHGNC:5122
MGIMGI:96192
EntrezGene (human)GeneID:3226
(SSTAR profile)
EntrezGene (mouse)GeneID:209448
(SSTAR profile)
UniProt ID (human)HXC10_HUMAN
UniProt ID (mouse)HXC10_MOUSE
UniProt AC (human)Q9NYD6
(TFClass)
UniProt AC (mouse)P31257
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 2 mouse
HT-SELEX 6
Methyl-HT-SELEX 2
PCM
ACGT
011276.51489.51527.51994.5
02868.75846.75810.753761.75
0325.017.0117.06129.0
041.00.00.06287.0
052810.00.00.03478.0
066288.00.00.00.0
070.01295.00.04993.0
080.00.06243.045.0
093764.00.02464.060.0
10123.02753.02387.01025.0
11747.52100.51783.51656.5
121065.751323.751501.752396.75
PFM
ACGT
010.2030.2370.2430.317
020.1380.1350.1290.598
030.0040.0030.0190.975
040.00.00.01.0
050.4470.00.00.553
061.00.00.00.0
070.00.2060.00.794
080.00.00.9930.007
090.5990.00.3920.01
100.020.4380.380.163
110.1190.3340.2840.263
120.1690.2110.2390.381
PWM
ACGT
01-0.208-0.054-0.0290.238
02-0.592-0.618-0.6610.872
03-4.059-4.407-2.5811.36
04-6.203-6.579-6.5791.385
050.58-6.579-6.5790.793
061.385-6.579-6.579-6.579
07-6.579-0.194-6.5791.155
08-6.579-6.5791.378-3.507
090.872-6.5790.449-3.231
10-2.5320.560.417-0.427
11-0.7420.2890.1260.052
12-0.388-0.172-0.0460.421
Standard thresholds
P-value Threshold
0.001 2.93797
0.0005 4.57597
0.0001 7.88349