MotifHXC10.H12CORE.2.SM.B
Gene (human)HOXC10
(GeneCards)
Gene synonyms (human)HOX3I
Gene (mouse)Hoxc10
Gene synonyms (mouse)Hox-3.6, Hoxc-10
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
B
Motif length12
ConsensusndTTTACGAYbn
GC content37.55%
Information content (bits; total / per base)13.674 / 1.139
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words8893

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 2 (10) 0.629 0.677 0.475 0.531 0.619 0.673 1.554 1.776 15.182 26.538

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.959 0.942 0.912 0.886 0.826 0.806
best 0.999 0.998 0.997 0.996 0.981 0.977
Methyl HT-SELEX, 2 experiments median 0.998 0.996 0.995 0.992 0.969 0.964
best 0.999 0.998 0.997 0.996 0.981 0.977
Non-Methyl HT-SELEX, 6 experiments median 0.895 0.857 0.833 0.791 0.742 0.717
best 0.996 0.994 0.989 0.984 0.956 0.946
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX9-13 {3.1.1.8} (TFClass)
TFClass IDTFClass: 3.1.1.8.7
HGNCHGNC:5122
MGIMGI:96192
EntrezGene (human)GeneID:3226
(SSTAR profile)
EntrezGene (mouse)GeneID:209448
(SSTAR profile)
UniProt ID (human)HXC10_HUMAN
UniProt ID (mouse)HXC10_MOUSE
UniProt AC (human)Q9NYD6
(TFClass)
UniProt AC (mouse)P31257
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 2 mouse
HT-SELEX 6
Methyl-HT-SELEX 2
PCM
ACGT
012318.751998.752851.751723.75
021543.25832.251209.255308.25
03268.029.0131.08465.0
0412.06.04.08871.0
05857.00.00.08036.0
068890.00.00.03.0
071.07526.00.01366.0
081.04.08633.0255.0
098703.011.0149.030.0
1013.05664.0959.02257.0
111068.04599.01908.01318.0
121821.01902.01660.03510.0
PFM
ACGT
010.2610.2250.3210.194
020.1740.0940.1360.597
030.030.0030.0150.952
040.0010.0010.00.998
050.0960.00.00.904
061.00.00.00.0
070.00.8460.00.154
080.00.00.9710.029
090.9790.0010.0170.003
100.0010.6370.1080.254
110.120.5170.2150.148
120.2050.2140.1870.395
PWM
ACGT
010.042-0.1060.249-0.254
02-0.365-0.981-0.6080.87
03-2.108-4.265-2.8151.336
04-5.049-5.595-5.8711.383
05-0.952-6.887-6.8871.284
061.385-6.887-6.887-6.045
07-6.5221.219-6.887-0.486
08-6.522-5.8711.356-2.158
091.364-5.122-2.689-4.234
10-4.9820.935-0.8390.015
11-0.7320.726-0.153-0.522
12-0.199-0.156-0.2920.456
Standard thresholds
P-value Threshold
0.001 2.34511
0.0005 3.82799
0.0001 6.988205