Motif | HXC10.H12CORE.2.SM.B |
Gene (human) | HOXC10 (GeneCards) |
Gene synonyms (human) | HOX3I |
Gene (mouse) | Hoxc10 |
Gene synonyms (mouse) | Hox-3.6, Hoxc-10 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 2 |
Quality | B |
Motif | HXC10.H12CORE.2.SM.B |
Gene (human) | HOXC10 (GeneCards) |
Gene synonyms (human) | HOX3I |
Gene (mouse) | Hoxc10 |
Gene synonyms (mouse) | Hox-3.6, Hoxc-10 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 2 |
Quality | B |
Motif length | 12 |
Consensus | ndTTTACGAYbn |
GC content | 37.55% |
Information content (bits; total / per base) | 13.674 / 1.139 |
Data sources | HT-SELEX + Methyl-HT-SELEX |
Aligned words | 8893 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Mouse | 2 (10) | 0.629 | 0.677 | 0.475 | 0.531 | 0.619 | 0.673 | 1.554 | 1.776 | 15.182 | 26.538 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 8 experiments | median | 0.959 | 0.942 | 0.912 | 0.886 | 0.826 | 0.806 |
best | 0.999 | 0.998 | 0.997 | 0.996 | 0.981 | 0.977 | |
Methyl HT-SELEX, 2 experiments | median | 0.998 | 0.996 | 0.995 | 0.992 | 0.969 | 0.964 |
best | 0.999 | 0.998 | 0.997 | 0.996 | 0.981 | 0.977 | |
Non-Methyl HT-SELEX, 6 experiments | median | 0.895 | 0.857 | 0.833 | 0.791 | 0.742 | 0.717 |
best | 0.996 | 0.994 | 0.989 | 0.984 | 0.956 | 0.946 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | HOX-related {3.1.1} (TFClass) |
TF subfamily | HOX9-13 {3.1.1.8} (TFClass) |
TFClass ID | TFClass: 3.1.1.8.7 |
HGNC | HGNC:5122 |
MGI | MGI:96192 |
EntrezGene (human) | GeneID:3226 (SSTAR profile) |
EntrezGene (mouse) | GeneID:209448 (SSTAR profile) |
UniProt ID (human) | HXC10_HUMAN |
UniProt ID (mouse) | HXC10_MOUSE |
UniProt AC (human) | Q9NYD6 (TFClass) |
UniProt AC (mouse) | P31257 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 2 mouse |
HT-SELEX | 6 |
Methyl-HT-SELEX | 2 |
PCM | HXC10.H12CORE.2.SM.B.pcm |
PWM | HXC10.H12CORE.2.SM.B.pwm |
PFM | HXC10.H12CORE.2.SM.B.pfm |
Alignment | HXC10.H12CORE.2.SM.B.words.tsv |
Threshold to P-value map | HXC10.H12CORE.2.SM.B.thr |
Motif in other formats | |
JASPAR format | HXC10.H12CORE.2.SM.B_jaspar_format.txt |
MEME format | HXC10.H12CORE.2.SM.B_meme_format.meme |
Transfac format | HXC10.H12CORE.2.SM.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 2318.75 | 1998.75 | 2851.75 | 1723.75 |
02 | 1543.25 | 832.25 | 1209.25 | 5308.25 |
03 | 268.0 | 29.0 | 131.0 | 8465.0 |
04 | 12.0 | 6.0 | 4.0 | 8871.0 |
05 | 857.0 | 0.0 | 0.0 | 8036.0 |
06 | 8890.0 | 0.0 | 0.0 | 3.0 |
07 | 1.0 | 7526.0 | 0.0 | 1366.0 |
08 | 1.0 | 4.0 | 8633.0 | 255.0 |
09 | 8703.0 | 11.0 | 149.0 | 30.0 |
10 | 13.0 | 5664.0 | 959.0 | 2257.0 |
11 | 1068.0 | 4599.0 | 1908.0 | 1318.0 |
12 | 1821.0 | 1902.0 | 1660.0 | 3510.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.261 | 0.225 | 0.321 | 0.194 |
02 | 0.174 | 0.094 | 0.136 | 0.597 |
03 | 0.03 | 0.003 | 0.015 | 0.952 |
04 | 0.001 | 0.001 | 0.0 | 0.998 |
05 | 0.096 | 0.0 | 0.0 | 0.904 |
06 | 1.0 | 0.0 | 0.0 | 0.0 |
07 | 0.0 | 0.846 | 0.0 | 0.154 |
08 | 0.0 | 0.0 | 0.971 | 0.029 |
09 | 0.979 | 0.001 | 0.017 | 0.003 |
10 | 0.001 | 0.637 | 0.108 | 0.254 |
11 | 0.12 | 0.517 | 0.215 | 0.148 |
12 | 0.205 | 0.214 | 0.187 | 0.395 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.042 | -0.106 | 0.249 | -0.254 |
02 | -0.365 | -0.981 | -0.608 | 0.87 |
03 | -2.108 | -4.265 | -2.815 | 1.336 |
04 | -5.049 | -5.595 | -5.871 | 1.383 |
05 | -0.952 | -6.887 | -6.887 | 1.284 |
06 | 1.385 | -6.887 | -6.887 | -6.045 |
07 | -6.522 | 1.219 | -6.887 | -0.486 |
08 | -6.522 | -5.871 | 1.356 | -2.158 |
09 | 1.364 | -5.122 | -2.689 | -4.234 |
10 | -4.982 | 0.935 | -0.839 | 0.015 |
11 | -0.732 | 0.726 | -0.153 | -0.522 |
12 | -0.199 | -0.156 | -0.292 | 0.456 |
P-value | Threshold |
---|---|
0.001 | 2.34511 |
0.0005 | 3.82799 |
0.0001 | 6.988205 |