Motif | HXC10.H12CORE.1.S.B |
Gene (human) | HOXC10 (GeneCards) |
Gene synonyms (human) | HOX3I |
Gene (mouse) | Hoxc10 |
Gene synonyms (mouse) | Hox-3.6, Hoxc-10 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif | HXC10.H12CORE.1.S.B |
Gene (human) | HOXC10 (GeneCards) |
Gene synonyms (human) | HOX3I |
Gene (mouse) | Hoxc10 |
Gene synonyms (mouse) | Hox-3.6, Hoxc-10 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif length | 12 |
Consensus | nhTTTATGRbbn |
GC content | 35.33% |
Information content (bits; total / per base) | 11.95 / 0.996 |
Data sources | HT-SELEX |
Aligned words | 6288 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Mouse | 2 (10) | 0.634 | 0.682 | 0.472 | 0.513 | 0.622 | 0.676 | 1.546 | 1.777 | 13.054 | 29.796 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 8 experiments | median | 0.951 | 0.92 | 0.922 | 0.886 | 0.852 | 0.822 |
best | 0.98 | 0.962 | 0.977 | 0.959 | 0.969 | 0.949 | |
Methyl HT-SELEX, 2 experiments | median | 0.976 | 0.955 | 0.972 | 0.95 | 0.958 | 0.935 |
best | 0.98 | 0.962 | 0.977 | 0.959 | 0.969 | 0.949 | |
Non-Methyl HT-SELEX, 6 experiments | median | 0.919 | 0.88 | 0.87 | 0.827 | 0.778 | 0.752 |
best | 0.974 | 0.954 | 0.967 | 0.944 | 0.949 | 0.923 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | HOX-related {3.1.1} (TFClass) |
TF subfamily | HOX9-13 {3.1.1.8} (TFClass) |
TFClass ID | TFClass: 3.1.1.8.7 |
HGNC | HGNC:5122 |
MGI | MGI:96192 |
EntrezGene (human) | GeneID:3226 (SSTAR profile) |
EntrezGene (mouse) | GeneID:209448 (SSTAR profile) |
UniProt ID (human) | HXC10_HUMAN |
UniProt ID (mouse) | HXC10_MOUSE |
UniProt AC (human) | Q9NYD6 (TFClass) |
UniProt AC (mouse) | P31257 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 2 mouse |
HT-SELEX | 6 |
Methyl-HT-SELEX | 2 |
PCM | HXC10.H12CORE.1.S.B.pcm |
PWM | HXC10.H12CORE.1.S.B.pwm |
PFM | HXC10.H12CORE.1.S.B.pfm |
Alignment | HXC10.H12CORE.1.S.B.words.tsv |
Threshold to P-value map | HXC10.H12CORE.1.S.B.thr |
Motif in other formats | |
JASPAR format | HXC10.H12CORE.1.S.B_jaspar_format.txt |
MEME format | HXC10.H12CORE.1.S.B_meme_format.meme |
Transfac format | HXC10.H12CORE.1.S.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 1276.5 | 1489.5 | 1527.5 | 1994.5 |
02 | 868.75 | 846.75 | 810.75 | 3761.75 |
03 | 25.0 | 17.0 | 117.0 | 6129.0 |
04 | 1.0 | 0.0 | 0.0 | 6287.0 |
05 | 2810.0 | 0.0 | 0.0 | 3478.0 |
06 | 6288.0 | 0.0 | 0.0 | 0.0 |
07 | 0.0 | 1295.0 | 0.0 | 4993.0 |
08 | 0.0 | 0.0 | 6243.0 | 45.0 |
09 | 3764.0 | 0.0 | 2464.0 | 60.0 |
10 | 123.0 | 2753.0 | 2387.0 | 1025.0 |
11 | 747.5 | 2100.5 | 1783.5 | 1656.5 |
12 | 1065.75 | 1323.75 | 1501.75 | 2396.75 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.203 | 0.237 | 0.243 | 0.317 |
02 | 0.138 | 0.135 | 0.129 | 0.598 |
03 | 0.004 | 0.003 | 0.019 | 0.975 |
04 | 0.0 | 0.0 | 0.0 | 1.0 |
05 | 0.447 | 0.0 | 0.0 | 0.553 |
06 | 1.0 | 0.0 | 0.0 | 0.0 |
07 | 0.0 | 0.206 | 0.0 | 0.794 |
08 | 0.0 | 0.0 | 0.993 | 0.007 |
09 | 0.599 | 0.0 | 0.392 | 0.01 |
10 | 0.02 | 0.438 | 0.38 | 0.163 |
11 | 0.119 | 0.334 | 0.284 | 0.263 |
12 | 0.169 | 0.211 | 0.239 | 0.381 |
A | C | G | T | |
---|---|---|---|---|
01 | -0.208 | -0.054 | -0.029 | 0.238 |
02 | -0.592 | -0.618 | -0.661 | 0.872 |
03 | -4.059 | -4.407 | -2.581 | 1.36 |
04 | -6.203 | -6.579 | -6.579 | 1.385 |
05 | 0.58 | -6.579 | -6.579 | 0.793 |
06 | 1.385 | -6.579 | -6.579 | -6.579 |
07 | -6.579 | -0.194 | -6.579 | 1.155 |
08 | -6.579 | -6.579 | 1.378 | -3.507 |
09 | 0.872 | -6.579 | 0.449 | -3.231 |
10 | -2.532 | 0.56 | 0.417 | -0.427 |
11 | -0.742 | 0.289 | 0.126 | 0.052 |
12 | -0.388 | -0.172 | -0.046 | 0.421 |
P-value | Threshold |
---|---|
0.001 | 2.93797 |
0.0005 | 4.57597 |
0.0001 | 7.88349 |