MotifHXC10.H12CORE.0.P.B
Gene (human)HOXC10
(GeneCards)
Gene synonyms (human)HOX3I
Gene (mouse)Hoxc10
Gene synonyms (mouse)Hox-3.6, Hoxc-10
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length11
ConsensusWGATTTATKdv
GC content29.51%
Information content (bits; total / per base)10.663 / 0.969
Data sourcesChIP-Seq
Aligned words976

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 2 (10) 0.758 0.848 0.686 0.781 0.77 0.855 2.797 3.442 67.203 106.071

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.765 0.699 0.703 0.653 0.634 0.61
best 0.874 0.815 0.822 0.766 0.745 0.705
Methyl HT-SELEX, 2 experiments median 0.853 0.791 0.802 0.744 0.728 0.689
best 0.874 0.815 0.822 0.766 0.741 0.705
Non-Methyl HT-SELEX, 6 experiments median 0.706 0.641 0.655 0.61 0.597 0.577
best 0.867 0.807 0.811 0.755 0.745 0.702
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX9-13 {3.1.1.8} (TFClass)
TFClass IDTFClass: 3.1.1.8.7
HGNCHGNC:5122
MGIMGI:96192
EntrezGene (human)GeneID:3226
(SSTAR profile)
EntrezGene (mouse)GeneID:209448
(SSTAR profile)
UniProt ID (human)HXC10_HUMAN
UniProt ID (mouse)HXC10_MOUSE
UniProt AC (human)Q9NYD6
(TFClass)
UniProt AC (mouse)P31257
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 2 mouse
HT-SELEX 6
Methyl-HT-SELEX 2
PCM
ACGT
01203.08.086.0679.0
0277.012.0820.067.0
03857.018.028.073.0
04100.019.033.0824.0
0569.09.019.0879.0
0626.025.088.0837.0
07894.023.044.015.0
089.0114.024.0829.0
09135.040.0533.0268.0
10314.083.0476.0103.0
11160.0407.0259.0150.0
PFM
ACGT
010.2080.0080.0880.696
020.0790.0120.840.069
030.8780.0180.0290.075
040.1020.0190.0340.844
050.0710.0090.0190.901
060.0270.0260.090.858
070.9160.0240.0450.015
080.0090.1170.0250.849
090.1380.0410.5460.275
100.3220.0850.4880.106
110.1640.4170.2650.154
PWM
ACGT
01-0.183-3.23-1.031.019
02-1.138-2.8851.207-1.274
031.251-2.523-2.112-1.19
04-0.882-2.473-1.9571.212
05-1.245-3.132-2.4731.277
06-2.182-2.219-1.0071.228
071.293-2.297-1.682-2.688
08-3.132-0.753-2.2571.218
09-0.586-1.7730.7780.093
100.251-1.0650.665-0.853
11-0.4180.5090.059-0.482
Standard thresholds
P-value Threshold
0.001 4.547735
0.0005 5.412165
0.0001 7.19243