Motif | HXB8.H12CORE.0.PSM.A |
Gene (human) | HOXB8 (GeneCards) |
Gene synonyms (human) | HOX2D |
Gene (mouse) | Hoxb8 |
Gene synonyms (mouse) | Hox-2.4, Hoxb-8 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | A |
Motif | HXB8.H12CORE.0.PSM.A |
Gene (human) | HOXB8 (GeneCards) |
Gene synonyms (human) | HOX2D |
Gene (mouse) | Hoxb8 |
Gene synonyms (mouse) | Hox-2.4, Hoxb-8 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | A |
Motif length | 12 |
Consensus | nhvbTAATKRbn |
GC content | 36.95% |
Information content (bits; total / per base) | 10.558 / 0.88 |
Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
Aligned words | 9673 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 1 (5) | 0.761 | 0.786 | 0.629 | 0.649 | 0.64 | 0.667 | 1.552 | 1.623 | 27.252 | 42.301 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 2 experiments | median | 0.934 | 0.898 | 0.895 | 0.854 | 0.834 | 0.795 |
best | 0.953 | 0.925 | 0.924 | 0.889 | 0.869 | 0.833 | |
Methyl HT-SELEX, 1 experiments | median | 0.915 | 0.871 | 0.866 | 0.819 | 0.799 | 0.758 |
best | 0.915 | 0.871 | 0.866 | 0.819 | 0.799 | 0.758 | |
Non-Methyl HT-SELEX, 1 experiments | median | 0.953 | 0.925 | 0.924 | 0.889 | 0.869 | 0.833 |
best | 0.953 | 0.925 | 0.924 | 0.889 | 0.869 | 0.833 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | HOX-related {3.1.1} (TFClass) |
TF subfamily | HOX8 {3.1.1.7} (TFClass) |
TFClass ID | TFClass: 3.1.1.7.1 |
HGNC | HGNC:5119 |
MGI | MGI:96189 |
EntrezGene (human) | GeneID:3218 (SSTAR profile) |
EntrezGene (mouse) | GeneID:15416 (SSTAR profile) |
UniProt ID (human) | HXB8_HUMAN |
UniProt ID (mouse) | HXB8_MOUSE |
UniProt AC (human) | P17481 (TFClass) |
UniProt AC (mouse) | P09632 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 1 human, 0 mouse |
HT-SELEX | 1 |
Methyl-HT-SELEX | 1 |
PCM | HXB8.H12CORE.0.PSM.A.pcm |
PWM | HXB8.H12CORE.0.PSM.A.pwm |
PFM | HXB8.H12CORE.0.PSM.A.pfm |
Alignment | HXB8.H12CORE.0.PSM.A.words.tsv |
Threshold to P-value map | HXB8.H12CORE.0.PSM.A.thr |
Motif in other formats | |
JASPAR format | HXB8.H12CORE.0.PSM.A_jaspar_format.txt |
MEME format | HXB8.H12CORE.0.PSM.A_meme_format.meme |
Transfac format | HXB8.H12CORE.0.PSM.A_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 2482.5 | 2356.5 | 2423.5 | 2410.5 |
02 | 1873.75 | 4139.75 | 1652.75 | 2006.75 |
03 | 2781.0 | 2582.0 | 3678.0 | 632.0 |
04 | 1080.0 | 1454.0 | 1651.0 | 5488.0 |
05 | 0.0 | 5.0 | 1.0 | 9667.0 |
06 | 9673.0 | 0.0 | 0.0 | 0.0 |
07 | 9673.0 | 0.0 | 0.0 | 0.0 |
08 | 0.0 | 102.0 | 1.0 | 9570.0 |
09 | 24.0 | 70.0 | 4949.0 | 4630.0 |
10 | 4144.0 | 119.0 | 4925.0 | 485.0 |
11 | 861.75 | 5643.75 | 1831.75 | 1335.75 |
12 | 2132.25 | 3146.25 | 2159.25 | 2235.25 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.257 | 0.244 | 0.251 | 0.249 |
02 | 0.194 | 0.428 | 0.171 | 0.207 |
03 | 0.288 | 0.267 | 0.38 | 0.065 |
04 | 0.112 | 0.15 | 0.171 | 0.567 |
05 | 0.0 | 0.001 | 0.0 | 0.999 |
06 | 1.0 | 0.0 | 0.0 | 0.0 |
07 | 1.0 | 0.0 | 0.0 | 0.0 |
08 | 0.0 | 0.011 | 0.0 | 0.989 |
09 | 0.002 | 0.007 | 0.512 | 0.479 |
10 | 0.428 | 0.012 | 0.509 | 0.05 |
11 | 0.089 | 0.583 | 0.189 | 0.138 |
12 | 0.22 | 0.325 | 0.223 | 0.231 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.026 | -0.026 | 0.002 | -0.003 |
02 | -0.255 | 0.537 | -0.38 | -0.186 |
03 | 0.14 | 0.065 | 0.419 | -1.339 |
04 | -0.805 | -0.508 | -0.381 | 0.819 |
05 | -6.961 | -5.805 | -6.6 | 1.385 |
06 | 1.386 | -6.961 | -6.961 | -6.961 |
07 | 1.386 | -6.961 | -6.961 | -6.961 |
08 | -6.961 | -3.145 | -6.6 | 1.375 |
09 | -4.522 | -3.511 | 0.716 | 0.649 |
10 | 0.538 | -2.994 | 0.711 | -1.603 |
11 | -1.03 | 0.847 | -0.277 | -0.593 |
12 | -0.126 | 0.263 | -0.113 | -0.079 |
P-value | Threshold |
---|---|
0.001 | 4.753685 |
0.0005 | 6.030275 |
0.0001 | 7.65123 |