MotifHXB7.H12INVITRO.1.SM.B
Gene (human)HOXB7
(GeneCards)
Gene synonyms (human)HOX2C
Gene (mouse)Hoxb7
Gene synonyms (mouse)Hox-2.3, Hoxb-7
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length11
ConsensusnvbTAATKvbn
GC content38.34%
Information content (bits; total / per base)8.447 / 0.768
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9377

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (7) 0.438 0.467 0.313 0.322 0.45 0.467 0.828 0.853 0 0

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.869 0.828 0.807 0.773 0.742 0.72
best 0.972 0.955 0.949 0.924 0.895 0.869
Methyl HT-SELEX, 2 experiments median 0.868 0.833 0.812 0.785 0.749 0.732
best 0.972 0.955 0.949 0.924 0.895 0.869
Non-Methyl HT-SELEX, 2 experiments median 0.869 0.828 0.807 0.773 0.742 0.72
best 0.948 0.916 0.922 0.883 0.872 0.833
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX6-7 {3.1.1.6} (TFClass)
TFClass IDTFClass: 3.1.1.6.5
HGNCHGNC:5118
MGIMGI:96188
EntrezGene (human)GeneID:3217
(SSTAR profile)
EntrezGene (mouse)GeneID:15415
(SSTAR profile)
UniProt ID (human)HXB7_HUMAN
UniProt ID (mouse)HXB7_MOUSE
UniProt AC (human)P09629
(TFClass)
UniProt AC (mouse)P09024
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 0 mouse
HT-SELEX 2
Methyl-HT-SELEX 2
PCM
ACGT
012166.752533.752501.752174.75
021825.02803.03776.0973.0
03821.01563.02629.04364.0
0429.0137.0254.08957.0
059349.00.028.00.0
069377.00.00.00.0
070.01026.0533.07818.0
0829.0240.05544.03564.0
093528.01060.03749.01040.0
101217.753687.752646.751824.75
112260.52575.52259.52281.5
PFM
ACGT
010.2310.270.2670.232
020.1950.2990.4030.104
030.0880.1670.280.465
040.0030.0150.0270.955
050.9970.00.0030.0
061.00.00.00.0
070.00.1090.0570.834
080.0030.0260.5910.38
090.3760.1130.40.111
100.130.3930.2820.195
110.2410.2750.2410.243
PWM
ACGT
01-0.0790.0780.065-0.075
02-0.250.1790.476-0.878
03-1.047-0.4050.1150.621
04-4.318-2.824-2.2141.34
051.383-6.934-4.35-6.934
061.386-6.934-6.934-6.934
07-6.934-0.825-1.4781.204
08-4.318-2.2710.860.419
090.408-0.7930.469-0.812
10-0.6540.4530.121-0.25
11-0.0360.094-0.037-0.027
Standard thresholds
P-value Threshold
0.001 5.45002
0.0005 6.16806
0.0001 7.213305