MotifHXB7.H12CORE.0.P.C
Gene (human)HOXB7
(GeneCards)
Gene synonyms (human)HOX2C
Gene (mouse)Hoxb7
Gene synonyms (mouse)Hox-2.3, Hoxb-7
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
C
Motif length14
ConsensusvTGATKSATKRnhb
GC content40.03%
Information content (bits; total / per base)11.861 / 0.847
Data sourcesChIP-Seq
Aligned words205

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (7) 0.766 0.874 0.76 0.846 0.76 0.85 3.444 3.926 34.509 88.602

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.535 0.519 0.533 0.518 0.524 0.515
best 0.604 0.563 0.589 0.554 0.569 0.544
Methyl HT-SELEX, 2 experiments median 0.533 0.519 0.529 0.517 0.521 0.513
best 0.573 0.542 0.563 0.537 0.546 0.529
Non-Methyl HT-SELEX, 2 experiments median 0.551 0.53 0.546 0.527 0.536 0.522
best 0.604 0.563 0.589 0.554 0.569 0.544
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX6-7 {3.1.1.6} (TFClass)
TFClass IDTFClass: 3.1.1.6.5
HGNCHGNC:5118
MGIMGI:96188
EntrezGene (human)GeneID:3217
(SSTAR profile)
EntrezGene (mouse)GeneID:15415
(SSTAR profile)
UniProt ID (human)HXB7_HUMAN
UniProt ID (mouse)HXB7_MOUSE
UniProt AC (human)P09629
(TFClass)
UniProt AC (mouse)P09024
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 0 mouse
HT-SELEX 2
Methyl-HT-SELEX 2
PCM
ACGT
01106.028.044.027.0
0227.02.011.0165.0
0312.03.0186.04.0
04196.01.04.04.0
055.020.07.0173.0
0614.04.054.0133.0
075.045.0142.013.0
08196.04.03.02.0
090.00.011.0194.0
1024.09.0117.055.0
1157.06.0112.030.0
1223.0100.059.023.0
1334.063.030.078.0
1436.045.039.085.0
PFM
ACGT
010.5170.1370.2150.132
020.1320.010.0540.805
030.0590.0150.9070.02
040.9560.0050.020.02
050.0240.0980.0340.844
060.0680.020.2630.649
070.0240.220.6930.063
080.9560.020.0150.01
090.00.00.0540.946
100.1170.0440.5710.268
110.2780.0290.5460.146
120.1120.4880.2880.112
130.1660.3070.1460.38
140.1760.220.190.415
PWM
ACGT
010.714-0.584-0.148-0.618
02-0.618-2.759-1.451.152
03-1.372-2.4971.271-2.289
041.323-3.116-2.289-2.289
05-2.117-0.902-1.8421.199
06-1.232-2.2890.0510.938
07-2.117-0.1271.003-1.3
081.323-2.289-2.497-2.759
09-3.677-3.677-1.451.312
10-0.73-1.6270.8110.069
110.104-1.970.768-0.518
12-0.7710.6560.137-0.771
13-0.3980.202-0.5180.411
14-0.343-0.127-0.2650.496
Standard thresholds
P-value Threshold
0.001 4.39371
0.0005 5.30306
0.0001 7.18751