MotifHXB6.H12INVITRO.0.SM.B
Gene (human)HOXB6
(GeneCards)
Gene synonyms (human)HOX2B
Gene (mouse)Hoxb6
Gene synonyms (mouse)Hox-2.2, Hoxb-6
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length13
ConsensusnhvYTAATGASbn
GC content38.43%
Information content (bits; total / per base)11.066 / 0.851
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words6765

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.862 0.816 0.811 0.77 0.734 0.709
best 0.952 0.922 0.918 0.883 0.828 0.804
Methyl HT-SELEX, 1 experiments median 0.952 0.922 0.918 0.883 0.828 0.804
best 0.952 0.922 0.918 0.883 0.828 0.804
Non-Methyl HT-SELEX, 1 experiments median 0.772 0.71 0.703 0.657 0.64 0.614
best 0.772 0.71 0.703 0.657 0.64 0.614
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX6-7 {3.1.1.6} (TFClass)
TFClass IDTFClass: 3.1.1.6.2
HGNCHGNC:5117
MGIMGI:96187
EntrezGene (human)GeneID:3216
(SSTAR profile)
EntrezGene (mouse)GeneID:15414
(SSTAR profile)
UniProt ID (human)HXB6_HUMAN
UniProt ID (mouse)HXB6_MOUSE
UniProt AC (human)P17509
(TFClass)
UniProt AC (mouse)P09023
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
011753.51642.51540.51828.5
021150.53048.51035.51530.5
032025.751482.752681.75574.75
04619.01148.0224.04774.0
050.01.00.06764.0
066765.00.00.00.0
076765.00.00.00.0
080.01741.00.05024.0
092.00.04161.02602.0
104460.03.02283.019.0
1189.54256.51350.51068.5
12837.752813.751465.751647.75
131816.51649.51265.52033.5
PFM
ACGT
010.2590.2430.2280.27
020.170.4510.1530.226
030.2990.2190.3960.085
040.0920.170.0330.706
050.00.00.01.0
061.00.00.00.0
071.00.00.00.0
080.00.2570.00.743
090.00.00.6150.385
100.6590.00.3370.003
110.0130.6290.20.158
120.1240.4160.2170.244
130.2690.2440.1870.301
PWM
ACGT
010.036-0.029-0.0930.078
02-0.3850.589-0.49-0.1
030.18-0.1310.461-1.077
04-1.003-0.387-2.0131.037
05-6.644-6.27-6.6441.385
061.385-6.644-6.644-6.644
071.385-6.644-6.644-6.644
08-6.6440.029-6.6441.088
09-5.998-6.6440.90.43
100.969-5.7850.3-4.38
11-2.9160.922-0.225-0.458
12-0.7010.509-0.143-0.026
130.071-0.025-0.290.184
Standard thresholds
P-value Threshold
0.001 4.44751
0.0005 5.84431
0.0001 7.698415