| Motif | HXB4.H12INVIVO.1.PSM.A |
| Gene (human) | HOXB4 (GeneCards) |
| Gene synonyms (human) | HOX2F |
| Gene (mouse) | Hoxb4 |
| Gene synonyms (mouse) | Hox-2.6, Hoxb-4 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | A |
| Motif | HXB4.H12INVIVO.1.PSM.A |
| Gene (human) | HOXB4 (GeneCards) |
| Gene synonyms (human) | HOX2F |
| Gene (mouse) | Hoxb4 |
| Gene synonyms (mouse) | Hox-2.6, Hoxb-4 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | A |
| Motif length | 9 |
| Consensus | RYWRATKRS |
| GC content | 36.77% |
| Information content (bits; total / per base) | 9.019 / 1.002 |
| Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 1000 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mouse | 3 (21) | 0.826 | 0.859 | 0.693 | 0.751 | 0.796 | 0.818 | 2.325 | 2.559 | 282.854 | 365.377 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 2 experiments | median | 0.872 | 0.819 | 0.801 | 0.759 | 0.717 | 0.695 |
| best | 0.911 | 0.861 | 0.873 | 0.821 | 0.806 | 0.763 | |
| Methyl HT-SELEX, 1 experiments | median | 0.833 | 0.778 | 0.73 | 0.696 | 0.628 | 0.626 |
| best | 0.833 | 0.778 | 0.73 | 0.696 | 0.628 | 0.626 | |
| Non-Methyl HT-SELEX, 1 experiments | median | 0.911 | 0.861 | 0.873 | 0.821 | 0.806 | 0.763 |
| best | 0.911 | 0.861 | 0.873 | 0.821 | 0.806 | 0.763 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | HOX-related {3.1.1} (TFClass) |
| TF subfamily | HOX4 {3.1.1.4} (TFClass) |
| TFClass ID | TFClass: 3.1.1.4.2 |
| HGNC | HGNC:5115 |
| MGI | MGI:96185 |
| EntrezGene (human) | GeneID:3214 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:15412 (SSTAR profile) |
| UniProt ID (human) | HXB4_HUMAN |
| UniProt ID (mouse) | HXB4_MOUSE |
| UniProt AC (human) | P17483 (TFClass) |
| UniProt AC (mouse) | P10284 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 3 mouse |
| HT-SELEX | 1 |
| Methyl-HT-SELEX | 1 |
| PCM | HXB4.H12INVIVO.1.PSM.A.pcm |
| PWM | HXB4.H12INVIVO.1.PSM.A.pwm |
| PFM | HXB4.H12INVIVO.1.PSM.A.pfm |
| Alignment | HXB4.H12INVIVO.1.PSM.A.words.tsv |
| Threshold to P-value map | HXB4.H12INVIVO.1.PSM.A.thr |
| Motif in other formats | |
| JASPAR format | HXB4.H12INVIVO.1.PSM.A_jaspar_format.txt |
| MEME format | HXB4.H12INVIVO.1.PSM.A_meme_format.meme |
| Transfac format | HXB4.H12INVIVO.1.PSM.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 648.0 | 134.0 | 163.0 | 55.0 |
| 02 | 28.0 | 327.0 | 64.0 | 581.0 |
| 03 | 146.0 | 11.0 | 117.0 | 726.0 |
| 04 | 682.0 | 7.0 | 295.0 | 16.0 |
| 05 | 1000.0 | 0.0 | 0.0 | 0.0 |
| 06 | 0.0 | 25.0 | 0.0 | 975.0 |
| 07 | 41.0 | 69.0 | 664.0 | 226.0 |
| 08 | 462.0 | 6.0 | 474.0 | 58.0 |
| 09 | 15.0 | 691.0 | 262.0 | 32.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.648 | 0.134 | 0.163 | 0.055 |
| 02 | 0.028 | 0.327 | 0.064 | 0.581 |
| 03 | 0.146 | 0.011 | 0.117 | 0.726 |
| 04 | 0.682 | 0.007 | 0.295 | 0.016 |
| 05 | 1.0 | 0.0 | 0.0 | 0.0 |
| 06 | 0.0 | 0.025 | 0.0 | 0.975 |
| 07 | 0.041 | 0.069 | 0.664 | 0.226 |
| 08 | 0.462 | 0.006 | 0.474 | 0.058 |
| 09 | 0.015 | 0.691 | 0.262 | 0.032 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.948 | -0.618 | -0.424 | -1.49 |
| 02 | -2.136 | 0.267 | -1.343 | 0.839 |
| 03 | -0.533 | -2.985 | -0.752 | 1.062 |
| 04 | 0.999 | -3.362 | 0.164 | -2.653 |
| 05 | 1.381 | -4.982 | -4.982 | -4.982 |
| 06 | -4.982 | -2.243 | -4.982 | 1.356 |
| 07 | -1.774 | -1.27 | 0.973 | -0.1 |
| 08 | 0.611 | -3.484 | 0.636 | -1.439 |
| 09 | -2.711 | 1.012 | 0.047 | -2.01 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.103385 |
| 0.0005 | 5.914615 |
| 0.0001 | 7.29157 |