MotifHXB4.H12CORE.1.PSM.A
Gene (human)HOXB4
(GeneCards)
Gene synonyms (human)HOX2F
Gene (mouse)Hoxb4
Gene synonyms (mouse)Hox-2.6, Hoxb-4
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
A
Motif length13
ConsensusnnvYTAATKAbnn
GC content36.35%
Information content (bits; total / per base)11.029 / 0.848
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words9826

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 3 (21) 0.7 0.74 0.569 0.59 0.674 0.743 1.958 2.137 135.959 198.119

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.951 0.928 0.874 0.856 0.771 0.771
best 0.972 0.954 0.953 0.929 0.893 0.869
Methyl HT-SELEX, 1 experiments median 0.93 0.903 0.795 0.784 0.649 0.673
best 0.93 0.903 0.795 0.784 0.649 0.673
Non-Methyl HT-SELEX, 1 experiments median 0.972 0.954 0.953 0.929 0.893 0.869
best 0.972 0.954 0.953 0.929 0.893 0.869
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX4 {3.1.1.4} (TFClass)
TFClass IDTFClass: 3.1.1.4.2
HGNCHGNC:5115
MGIMGI:96185
EntrezGene (human)GeneID:3214
(SSTAR profile)
EntrezGene (mouse)GeneID:15412
(SSTAR profile)
UniProt ID (human)HXB4_HUMAN
UniProt ID (mouse)HXB4_MOUSE
UniProt AC (human)P17483
(TFClass)
UniProt AC (mouse)P10284
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 3 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
013369.251949.252413.252094.25
021789.753793.752228.752013.75
032278.02399.04796.0353.0
04413.03865.0662.04886.0
050.03.013.09810.0
069821.00.05.00.0
079825.00.01.00.0
081.0523.012.09290.0
098.052.05565.04201.0
107929.039.01791.067.0
11947.03555.01774.03550.0
121485.753397.752667.752274.75
132313.02683.02240.02590.0
PFM
ACGT
010.3430.1980.2460.213
020.1820.3860.2270.205
030.2320.2440.4880.036
040.0420.3930.0670.497
050.00.00.0010.998
060.9990.00.0010.0
071.00.00.00.0
080.00.0530.0010.945
090.0010.0050.5660.428
100.8070.0040.1820.007
110.0960.3620.1810.361
120.1510.3460.2710.232
130.2350.2730.2280.264
PWM
ACGT
010.316-0.231-0.018-0.159
02-0.3160.434-0.097-0.199
03-0.075-0.0240.669-1.934
04-1.7780.453-1.3090.687
05-6.975-6.14-5.081.384
061.385-6.975-5.82-6.975
071.385-6.975-6.614-6.975
08-6.614-1.543-5.1471.33
09-5.475-3.8130.8170.536
101.171-4.087-0.316-3.569
11-0.9520.369-0.3250.368
12-0.5020.3240.082-0.077
13-0.060.088-0.0920.053
Standard thresholds
P-value Threshold
0.001 4.15361
0.0005 5.68571
0.0001 7.84422