Motif | HXB4.H12CORE.1.PSM.A |
Gene (human) | HOXB4 (GeneCards) |
Gene synonyms (human) | HOX2F |
Gene (mouse) | Hoxb4 |
Gene synonyms (mouse) | Hox-2.6, Hoxb-4 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | A |
Motif | HXB4.H12CORE.1.PSM.A |
Gene (human) | HOXB4 (GeneCards) |
Gene synonyms (human) | HOX2F |
Gene (mouse) | Hoxb4 |
Gene synonyms (mouse) | Hox-2.6, Hoxb-4 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | A |
Motif length | 13 |
Consensus | nnvYTAATKAbnn |
GC content | 36.35% |
Information content (bits; total / per base) | 11.029 / 0.848 |
Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
Aligned words | 9826 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Mouse | 3 (21) | 0.7 | 0.74 | 0.569 | 0.59 | 0.674 | 0.743 | 1.958 | 2.137 | 135.959 | 198.119 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 2 experiments | median | 0.951 | 0.928 | 0.874 | 0.856 | 0.771 | 0.771 |
best | 0.972 | 0.954 | 0.953 | 0.929 | 0.893 | 0.869 | |
Methyl HT-SELEX, 1 experiments | median | 0.93 | 0.903 | 0.795 | 0.784 | 0.649 | 0.673 |
best | 0.93 | 0.903 | 0.795 | 0.784 | 0.649 | 0.673 | |
Non-Methyl HT-SELEX, 1 experiments | median | 0.972 | 0.954 | 0.953 | 0.929 | 0.893 | 0.869 |
best | 0.972 | 0.954 | 0.953 | 0.929 | 0.893 | 0.869 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | HOX-related {3.1.1} (TFClass) |
TF subfamily | HOX4 {3.1.1.4} (TFClass) |
TFClass ID | TFClass: 3.1.1.4.2 |
HGNC | HGNC:5115 |
MGI | MGI:96185 |
EntrezGene (human) | GeneID:3214 (SSTAR profile) |
EntrezGene (mouse) | GeneID:15412 (SSTAR profile) |
UniProt ID (human) | HXB4_HUMAN |
UniProt ID (mouse) | HXB4_MOUSE |
UniProt AC (human) | P17483 (TFClass) |
UniProt AC (mouse) | P10284 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 3 mouse |
HT-SELEX | 1 |
Methyl-HT-SELEX | 1 |
PCM | HXB4.H12CORE.1.PSM.A.pcm |
PWM | HXB4.H12CORE.1.PSM.A.pwm |
PFM | HXB4.H12CORE.1.PSM.A.pfm |
Alignment | HXB4.H12CORE.1.PSM.A.words.tsv |
Threshold to P-value map | HXB4.H12CORE.1.PSM.A.thr |
Motif in other formats | |
JASPAR format | HXB4.H12CORE.1.PSM.A_jaspar_format.txt |
MEME format | HXB4.H12CORE.1.PSM.A_meme_format.meme |
Transfac format | HXB4.H12CORE.1.PSM.A_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 3369.25 | 1949.25 | 2413.25 | 2094.25 |
02 | 1789.75 | 3793.75 | 2228.75 | 2013.75 |
03 | 2278.0 | 2399.0 | 4796.0 | 353.0 |
04 | 413.0 | 3865.0 | 662.0 | 4886.0 |
05 | 0.0 | 3.0 | 13.0 | 9810.0 |
06 | 9821.0 | 0.0 | 5.0 | 0.0 |
07 | 9825.0 | 0.0 | 1.0 | 0.0 |
08 | 1.0 | 523.0 | 12.0 | 9290.0 |
09 | 8.0 | 52.0 | 5565.0 | 4201.0 |
10 | 7929.0 | 39.0 | 1791.0 | 67.0 |
11 | 947.0 | 3555.0 | 1774.0 | 3550.0 |
12 | 1485.75 | 3397.75 | 2667.75 | 2274.75 |
13 | 2313.0 | 2683.0 | 2240.0 | 2590.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.343 | 0.198 | 0.246 | 0.213 |
02 | 0.182 | 0.386 | 0.227 | 0.205 |
03 | 0.232 | 0.244 | 0.488 | 0.036 |
04 | 0.042 | 0.393 | 0.067 | 0.497 |
05 | 0.0 | 0.0 | 0.001 | 0.998 |
06 | 0.999 | 0.0 | 0.001 | 0.0 |
07 | 1.0 | 0.0 | 0.0 | 0.0 |
08 | 0.0 | 0.053 | 0.001 | 0.945 |
09 | 0.001 | 0.005 | 0.566 | 0.428 |
10 | 0.807 | 0.004 | 0.182 | 0.007 |
11 | 0.096 | 0.362 | 0.181 | 0.361 |
12 | 0.151 | 0.346 | 0.271 | 0.232 |
13 | 0.235 | 0.273 | 0.228 | 0.264 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.316 | -0.231 | -0.018 | -0.159 |
02 | -0.316 | 0.434 | -0.097 | -0.199 |
03 | -0.075 | -0.024 | 0.669 | -1.934 |
04 | -1.778 | 0.453 | -1.309 | 0.687 |
05 | -6.975 | -6.14 | -5.08 | 1.384 |
06 | 1.385 | -6.975 | -5.82 | -6.975 |
07 | 1.385 | -6.975 | -6.614 | -6.975 |
08 | -6.614 | -1.543 | -5.147 | 1.33 |
09 | -5.475 | -3.813 | 0.817 | 0.536 |
10 | 1.171 | -4.087 | -0.316 | -3.569 |
11 | -0.952 | 0.369 | -0.325 | 0.368 |
12 | -0.502 | 0.324 | 0.082 | -0.077 |
13 | -0.06 | 0.088 | -0.092 | 0.053 |
P-value | Threshold |
---|---|
0.001 | 4.15361 |
0.0005 | 5.68571 |
0.0001 | 7.84422 |