MotifHXB4.H12CORE.0.P.B
Gene (human)HOXB4
(GeneCards)
Gene synonyms (human)HOX2F
Gene (mouse)Hoxb4
Gene synonyms (mouse)Hox-2.6, Hoxb-4
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length9
ConsensusTGAYKRATK
GC content33.01%
Information content (bits; total / per base)8.922 / 0.991
Data sourcesChIP-Seq
Aligned words1000

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 3 (21) 0.742 0.802 0.638 0.727 0.739 0.789 2.343 2.902 223.959 311.076

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.75 0.681 0.688 0.642 0.625 0.603
best 0.813 0.732 0.761 0.697 0.694 0.652
Methyl HT-SELEX, 1 experiments median 0.687 0.63 0.615 0.588 0.557 0.555
best 0.687 0.63 0.615 0.588 0.557 0.555
Non-Methyl HT-SELEX, 1 experiments median 0.813 0.732 0.761 0.697 0.694 0.652
best 0.813 0.732 0.761 0.697 0.694 0.652
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX4 {3.1.1.4} (TFClass)
TFClass IDTFClass: 3.1.1.4.2
HGNCHGNC:5115
MGIMGI:96185
EntrezGene (human)GeneID:3214
(SSTAR profile)
EntrezGene (mouse)GeneID:15412
(SSTAR profile)
UniProt ID (human)HXB4_HUMAN
UniProt ID (mouse)HXB4_MOUSE
UniProt AC (human)P17483
(TFClass)
UniProt AC (mouse)P10284
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 3 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
0191.07.025.0877.0
02218.09.0760.013.0
03934.048.014.04.0
0418.0166.060.0756.0
05156.09.0300.0535.0
06419.022.0511.048.0
07720.0270.05.05.0
0844.039.032.0885.0
09101.081.0613.0205.0
PFM
ACGT
010.0910.0070.0250.877
020.2180.0090.760.013
030.9340.0480.0140.004
040.0180.1660.060.756
050.1560.0090.30.535
060.4190.0220.5110.048
070.720.270.0050.005
080.0440.0390.0320.885
090.1010.0810.6130.205
PWM
ACGT
01-0.999-3.362-2.2431.25
02-0.136-3.1561.107-2.839
031.313-1.622-2.773-3.783
04-2.546-0.406-1.4061.102
05-0.467-3.1560.1810.757
060.514-2.3620.711-1.622
071.0530.076-3.622-3.622
08-1.706-1.821-2.011.259
09-0.896-1.1130.893-0.197
Standard thresholds
P-value Threshold
0.001 4.92948
0.0005 5.737735
0.0001 7.23583