MotifHXB2.H12CORE.0.SM.B
Gene (human)HOXB2
(GeneCards)
Gene synonyms (human)HOX2H
Gene (mouse)Hoxb2
Gene synonyms (mouse)Hox-2.8
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length12
ConsensusnvvYTAATKRbn
GC content38.62%
Information content (bits; total / per base)11.188 / 0.932
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words8768

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.986 0.978 0.976 0.962 0.949 0.93
best 0.992 0.987 0.983 0.974 0.97 0.956
Methyl HT-SELEX, 1 experiments median 0.99 0.984 0.983 0.973 0.97 0.956
best 0.99 0.984 0.983 0.973 0.97 0.956
Non-Methyl HT-SELEX, 3 experiments median 0.982 0.972 0.97 0.952 0.948 0.926
best 0.992 0.987 0.982 0.974 0.949 0.935
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX2 {3.1.1.2} (TFClass)
TFClass IDTFClass: 3.1.1.2.2
HGNCHGNC:5113
MGIMGI:96183
EntrezGene (human)GeneID:3212
(SSTAR profile)
EntrezGene (mouse)GeneID:103889
(SSTAR profile)
UniProt ID (human)HXB2_HUMAN
UniProt ID (mouse)HXB2_MOUSE
UniProt AC (human)P14652
(TFClass)
UniProt AC (mouse)P0C1T1
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
012192.02212.02387.01977.0
021478.253845.251973.251471.25
032175.02301.03923.0369.0
0492.05010.0810.02856.0
050.00.00.08768.0
068768.00.00.00.0
078768.00.00.00.0
080.01.01.08766.0
093.0181.04089.04495.0
106547.0140.01893.0188.0
11738.254186.252455.251388.25
121621.02570.02657.01920.0
PFM
ACGT
010.250.2520.2720.225
020.1690.4390.2250.168
030.2480.2620.4470.042
040.010.5710.0920.326
050.00.00.01.0
061.00.00.00.0
071.00.00.00.0
080.00.00.01.0
090.00.0210.4660.513
100.7470.0160.2160.021
110.0840.4770.280.158
120.1850.2930.3030.219
PWM
ACGT
010.00.0090.085-0.103
02-0.3930.562-0.105-0.398
03-0.0080.0480.582-1.777
04-3.1470.826-0.9940.264
05-6.874-6.874-6.8741.386
061.386-6.874-6.874-6.874
071.386-6.874-6.874-6.874
08-6.874-6.509-6.5091.385
09-6.032-2.4830.6230.718
101.094-2.736-0.146-2.445
11-1.0860.6460.113-0.456
12-0.3010.1590.192-0.132
Standard thresholds
P-value Threshold
0.001 4.06156
0.0005 5.60036
0.0001 7.83836