MotifHXB13.H12INVITRO.0.PS.A
Gene (human)HOXB13
(GeneCards)
Gene synonyms (human)
Gene (mouse)Hoxb13
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length12
ConsensusnKTTTAYKRGbn
GC content37.9%
Information content (bits; total / per base)11.565 / 0.964
Data sourcesChIP-Seq + HT-SELEX
Aligned words9981

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 21 (108) 0.844 0.948 0.708 0.886 0.779 0.904 2.254 3.234 81.293 391.31

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.983 0.973 0.952 0.938 0.869 0.867
best 0.997 0.995 0.993 0.99 0.984 0.978
Methyl HT-SELEX, 1 experiments median 0.997 0.995 0.993 0.99 0.984 0.978
best 0.997 0.995 0.993 0.99 0.984 0.978
Non-Methyl HT-SELEX, 3 experiments median 0.972 0.958 0.918 0.897 0.77 0.777
best 0.993 0.988 0.987 0.98 0.969 0.957

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 20.559 8.796 0.325 0.215
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX9-13 {3.1.1.8} (TFClass)
TFClass IDTFClass: 3.1.1.8.15
HGNCHGNC:5112
MGIMGI:107730
EntrezGene (human)GeneID:10481
(SSTAR profile)
EntrezGene (mouse)GeneID:15408
(SSTAR profile)
UniProt ID (human)HXB13_HUMAN
UniProt ID (mouse)HXB13_MOUSE
UniProt AC (human)Q92826
(TFClass)
UniProt AC (mouse)P70321
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 21 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
012121.51719.53482.52657.5
02948.25856.251983.256193.25
03159.092.0189.09541.0
04164.033.034.09750.0
05864.043.021.09053.0
069962.03.04.012.0
0730.04886.01.05064.0
08413.022.07173.02373.0
096285.075.03505.0116.0
10263.01037.08147.0534.0
111379.53284.53560.51756.5
121598.252819.252423.253140.25
PFM
ACGT
010.2130.1720.3490.266
020.0950.0860.1990.621
030.0160.0090.0190.956
040.0160.0030.0030.977
050.0870.0040.0020.907
060.9980.00.00.001
070.0030.490.00.507
080.0410.0020.7190.238
090.630.0080.3510.012
100.0260.1040.8160.054
110.1380.3290.3570.176
120.160.2820.2430.315
PWM
ACGT
01-0.162-0.3720.3330.063
02-0.966-1.068-0.2290.909
03-2.74-3.277-2.5691.341
04-2.709-4.259-4.2311.362
05-1.059-4.01-4.6751.288
061.384-6.155-5.982-5.163
07-4.3480.672-6.6290.707
08-1.794-4.6331.055-0.05
090.923-3.4750.34-3.05
10-2.242-0.8771.183-1.538
11-0.5920.2750.355-0.351
12-0.4450.122-0.0290.23
Standard thresholds
P-value Threshold
0.001 4.09236
0.0005 5.217065
0.0001 7.48429