MotifHXB13.H12CORE.1.SM.B
Gene (human)HOXB13
(GeneCards)
Gene synonyms (human)
Gene (mouse)Hoxb13
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length12
ConsensusndTTTACGAGvn
GC content41.55%
Information content (bits; total / per base)14.45 / 1.204
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words7712

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 21 (108) 0.785 0.855 0.646 0.751 0.708 0.769 1.981 2.471 45.551 165.77

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.967 0.958 0.919 0.904 0.837 0.83
best 0.999 0.998 0.998 0.997 0.992 0.989
Methyl HT-SELEX, 1 experiments median 0.999 0.998 0.998 0.997 0.992 0.989
best 0.999 0.998 0.998 0.997 0.992 0.989
Non-Methyl HT-SELEX, 3 experiments median 0.938 0.922 0.852 0.827 0.734 0.729
best 0.996 0.994 0.986 0.981 0.94 0.931

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 5.333 4.488 0.25 0.119
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX9-13 {3.1.1.8} (TFClass)
TFClass IDTFClass: 3.1.1.8.15
HGNCHGNC:5112
MGIMGI:107730
EntrezGene (human)GeneID:10481
(SSTAR profile)
EntrezGene (mouse)GeneID:15408
(SSTAR profile)
UniProt ID (human)HXB13_HUMAN
UniProt ID (mouse)HXB13_MOUSE
UniProt AC (human)Q92826
(TFClass)
UniProt AC (mouse)P70321
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 21 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
012070.251288.252795.251558.25
021417.0608.02032.03655.0
0385.024.0132.07471.0
0429.07.09.07667.0
05447.03.01.07261.0
067712.00.00.00.0
070.07027.00.0685.0
0853.02.07603.054.0
097496.035.0148.033.0
1032.0459.06859.0362.0
111146.252585.253021.25959.25
121573.751700.752107.752329.75
PFM
ACGT
010.2680.1670.3620.202
020.1840.0790.2630.474
030.0110.0030.0170.969
040.0040.0010.0010.994
050.0580.00.00.942
061.00.00.00.0
070.00.9110.00.089
080.0070.00.9860.007
090.9720.0050.0190.004
100.0040.060.8890.047
110.1490.3350.3920.124
120.2040.2210.2730.302
PWM
ACGT
010.071-0.4030.371-0.213
02-0.308-1.1520.0520.639
03-3.097-4.298-2.6661.354
04-4.124-5.342-5.1461.38
05-1.458-5.91-6.3911.325
061.385-6.76-6.76-6.76
07-6.761.292-6.76-1.033
08-3.554-6.1211.371-3.536
091.357-3.948-2.553-4.003
10-4.032-1.4311.268-1.668
11-0.5190.2930.449-0.697
12-0.203-0.1250.0890.189
Standard thresholds
P-value Threshold
0.001 1.99167
0.0005 3.449285
0.0001 6.483895