MotifHXB1.H12CORE.0.SM.B
Gene (human)HOXB1
(GeneCards)
Gene synonyms (human)HOX2I
Gene (mouse)Hoxb1
Gene synonyms (mouse)Hox-2.9, Hoxb-1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length12
ConsensusnnvYTAATYAvn
GC content34.7%
Information content (bits; total / per base)11.153 / 0.929
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words7459

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.938 0.903 0.903 0.863 0.836 0.803
best 0.954 0.926 0.934 0.899 0.891 0.854
Methyl HT-SELEX, 1 experiments median 0.921 0.879 0.872 0.827 0.782 0.752
best 0.921 0.879 0.872 0.827 0.782 0.752
Non-Methyl HT-SELEX, 1 experiments median 0.954 0.926 0.934 0.899 0.891 0.854
best 0.954 0.926 0.934 0.899 0.891 0.854
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX1 {3.1.1.1} (TFClass)
TFClass IDTFClass: 3.1.1.1.2
HGNCHGNC:5111
MGIMGI:96182
EntrezGene (human)GeneID:3211
(SSTAR profile)
EntrezGene (mouse)GeneID:15407
(SSTAR profile)
UniProt ID (human)HXB1_HUMAN
UniProt ID (mouse)HXB1_MOUSE
UniProt AC (human)P14653
(TFClass)
UniProt AC (mouse)P17919
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
011683.01716.01757.02303.0
021517.02515.02169.01258.0
031559.02270.03416.0214.0
048.03155.01536.02760.0
050.00.00.07459.0
067459.00.00.00.0
077459.00.00.00.0
080.00.00.07459.0
090.01020.0841.05598.0
105798.024.01609.028.0
111161.253130.252182.25985.25
121695.51914.51800.52048.5
PFM
ACGT
010.2260.230.2360.309
020.2030.3370.2910.169
030.2090.3040.4580.029
040.0010.4230.2060.37
050.00.00.01.0
061.00.00.00.0
071.00.00.00.0
080.00.00.01.0
090.00.1370.1130.751
100.7770.0030.2160.004
110.1560.420.2930.132
120.2270.2570.2410.275
PWM
ACGT
01-0.102-0.083-0.0590.211
02-0.2060.2990.151-0.393
03-0.1790.1960.605-2.156
04-5.2070.525-0.1940.392
05-6.73-6.73-6.731.385
061.385-6.73-6.73-6.73
071.385-6.73-6.73-6.73
08-6.73-6.73-6.731.385
09-6.73-0.602-0.7951.098
101.134-4.265-0.147-4.123
11-0.4730.5180.157-0.637
12-0.0950.026-0.0350.094
Standard thresholds
P-value Threshold
0.001 3.66915
0.0005 5.875245
0.0001 7.82252