MotifHXA9.H12CORE.1.SM.B
Gene (human)HOXA9
(GeneCards)
Gene synonyms (human)HOX1G
Gene (mouse)Hoxa9
Gene synonyms (mouse)Hox-1.7, Hoxa-9
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length11
ConsensusnKTAATGRSvn
GC content41.07%
Information content (bits; total / per base)9.914 / 0.901
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words8730

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 4 (24) 0.74 0.813 0.544 0.651 0.677 0.742 1.522 1.787 18.808 40.252
Mouse 5 (32) 0.598 0.771 0.425 0.596 0.494 0.67 1.019 1.558 16.305 68.77

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.929 0.883 0.912 0.863 0.883 0.833
best 0.944 0.905 0.929 0.886 0.905 0.859
Methyl HT-SELEX, 1 experiments median 0.944 0.905 0.929 0.886 0.905 0.859
best 0.944 0.905 0.929 0.886 0.905 0.859
Non-Methyl HT-SELEX, 1 experiments median 0.914 0.861 0.896 0.84 0.862 0.807
best 0.914 0.861 0.896 0.84 0.862 0.807
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX9-13 {3.1.1.8} (TFClass)
TFClass IDTFClass: 3.1.1.8.1
HGNCHGNC:5109
MGIMGI:96180
EntrezGene (human)GeneID:3205
(SSTAR profile)
EntrezGene (mouse)GeneID:15405
(SSTAR profile)
UniProt ID (human)HXA9_HUMAN
UniProt ID (mouse)HXA9_MOUSE
UniProt AC (human)P31269
(TFClass)
UniProt AC (mouse)P09631
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 4 human, 5 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
011907.252450.252865.251507.25
02753.0244.01763.05970.0
0324.01.00.08705.0
046467.00.04.02259.0
058730.00.00.00.0
060.03681.00.05049.0
077.012.08306.0405.0
085218.042.03028.0442.0
09202.04633.02035.01860.0
101448.03324.02610.01348.0
112180.52372.52072.52104.5
PFM
ACGT
010.2180.2810.3280.173
020.0860.0280.2020.684
030.0030.00.00.997
040.7410.00.00.259
051.00.00.00.0
060.00.4220.00.578
070.0010.0010.9510.046
080.5980.0050.3470.051
090.0230.5310.2330.213
100.1660.3810.2990.154
110.250.2720.2370.241
PWM
ACGT
01-0.1350.1160.272-0.37
02-1.062-2.183-0.2131.006
03-4.421-6.505-6.871.383
041.086-6.87-5.8540.034
051.386-6.87-6.87-6.87
06-6.870.522-6.870.838
07-5.463-5.0311.336-1.68
080.871-3.8990.327-1.593
09-2.370.752-0.07-0.16
10-0.410.420.179-0.481
11-0.0010.083-0.052-0.036
Standard thresholds
P-value Threshold
0.001 5.069335
0.0005 6.08659
0.0001 7.6069