MotifHXA6.H12CORE.0.SM.B
Gene (human)HOXA6
(GeneCards)
Gene synonyms (human)HOX1B
Gene (mouse)Hoxa6
Gene synonyms (mouse)Hox-1.2, Hoxa-6
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length12
ConsensusnvbTAATKRbnn
GC content35.8%
Information content (bits; total / per base)10.302 / 0.859
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9530

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.896 0.842 0.853 0.799 0.788 0.745
best 0.91 0.859 0.881 0.826 0.832 0.781
Methyl HT-SELEX, 1 experiments median 0.882 0.825 0.826 0.773 0.744 0.709
best 0.882 0.825 0.826 0.773 0.744 0.709
Non-Methyl HT-SELEX, 1 experiments median 0.91 0.859 0.881 0.826 0.832 0.781
best 0.91 0.859 0.881 0.826 0.832 0.781
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX6-7 {3.1.1.6} (TFClass)
TFClass IDTFClass: 3.1.1.6.1
HGNCHGNC:5107
MGIMGI:96178
EntrezGene (human)GeneID:3203
(SSTAR profile)
EntrezGene (mouse)GeneID:15403
(SSTAR profile)
UniProt ID (human)HXA6_HUMAN
UniProt ID (mouse)HXA6_MOUSE
UniProt AC (human)P31267
(TFClass)
UniProt AC (mouse)P09092
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
012282.03019.02098.02131.0
023166.52267.52974.51121.5
031029.01817.01506.05178.0
046.08.00.09516.0
059530.00.00.00.0
069530.00.00.00.0
070.0166.00.09364.0
0875.0152.04758.04545.0
094910.081.04249.0290.0
10696.05144.02293.01397.0
111528.03637.02083.02282.0
122403.52679.52010.52436.5
PFM
ACGT
010.2390.3170.220.224
020.3320.2380.3120.118
030.1080.1910.1580.543
040.0010.0010.00.999
051.00.00.00.0
061.00.00.00.0
070.00.0170.00.983
080.0080.0160.4990.477
090.5150.0080.4460.03
100.0730.540.2410.147
110.160.3820.2190.239
120.2520.2810.2110.256
PWM
ACGT
01-0.0430.237-0.127-0.111
020.284-0.0490.222-0.752
03-0.838-0.271-0.4580.776
04-5.662-5.446-6.9481.384
051.386-6.948-6.948-6.948
061.386-6.948-6.948-6.948
07-6.948-2.651-6.9481.368
08-3.429-2.7380.6910.645
090.723-3.3550.578-2.099
10-1.2280.769-0.038-0.533
11-0.4440.423-0.134-0.043
120.0090.117-0.170.022
Standard thresholds
P-value Threshold
0.001 4.766665
0.0005 6.19002
0.0001 7.66365