MotifHXA5.H12CORE.0.SM.B
Gene (human)HOXA5
(GeneCards)
Gene synonyms (human)HOX1C
Gene (mouse)Hoxa5
Gene synonyms (mouse)Hox-1.3, Hoxa-5
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length12
ConsensusnnvbTAATKRbn
GC content37.44%
Information content (bits; total / per base)10.382 / 0.865
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9703

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.956 0.932 0.927 0.894 0.864 0.832
best 0.966 0.946 0.94 0.912 0.883 0.854
Methyl HT-SELEX, 2 experiments median 0.959 0.936 0.925 0.894 0.848 0.823
best 0.966 0.946 0.94 0.912 0.883 0.854
Non-Methyl HT-SELEX, 2 experiments median 0.956 0.932 0.927 0.894 0.864 0.832
best 0.959 0.935 0.932 0.9 0.875 0.843
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX5 {3.1.1.5} (TFClass)
TFClass IDTFClass: 3.1.1.5.1
HGNCHGNC:5106
MGIMGI:96177
EntrezGene (human)GeneID:3202
(SSTAR profile)
EntrezGene (mouse)GeneID:15402
(SSTAR profile)
UniProt ID (human)HXA5_HUMAN
UniProt ID (mouse)HXA5_MOUSE
UniProt AC (human)P20719
(TFClass)
UniProt AC (mouse)P09021
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 2
Methyl-HT-SELEX 2
PCM
ACGT
013005.251930.252337.252430.25
021915.53818.51949.52019.5
032103.03117.04118.0365.0
04426.03891.01852.03534.0
050.01.02.09700.0
069703.00.00.00.0
079703.00.00.00.0
080.042.00.09661.0
0923.0303.04778.04599.0
106016.0242.03072.0373.0
11972.54579.52228.51922.5
122113.252818.252513.252258.25
PFM
ACGT
010.310.1990.2410.25
020.1970.3940.2010.208
030.2170.3210.4240.038
040.0440.4010.1910.364
050.00.00.01.0
061.00.00.00.0
071.00.00.00.0
080.00.0040.00.996
090.0020.0310.4920.474
100.620.0250.3170.038
110.10.4720.230.198
120.2180.290.2590.233
PWM
ACGT
010.214-0.228-0.0370.002
02-0.2360.453-0.218-0.183
03-0.1430.2510.529-1.889
04-1.7350.472-0.270.376
05-6.964-6.602-6.3371.385
061.386-6.964-6.964-6.964
071.386-6.964-6.964-6.964
08-6.964-4.004-6.9641.381
09-4.564-2.0740.6770.639
100.908-2.2960.236-1.867
11-0.9130.635-0.085-0.232
12-0.1380.150.035-0.071
Standard thresholds
P-value Threshold
0.001 4.76111
0.0005 6.099665
0.0001 7.745095