MotifHXA4.H12INVITRO.0.SM.B
Gene (human)HOXA4
(GeneCards)
Gene synonyms (human)HOX1D
Gene (mouse)Hoxa4
Gene synonyms (mouse)Hox-1.4, Hoxa-4
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length12
ConsensusnnvYTAATKRbn
GC content36.78%
Information content (bits; total / per base)10.328 / 0.861
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9562

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.953 0.923 0.93 0.894 0.863 0.832
best 0.957 0.93 0.933 0.9 0.869 0.833
Methyl HT-SELEX, 1 experiments median 0.957 0.93 0.933 0.9 0.858 0.831
best 0.957 0.93 0.933 0.9 0.858 0.831
Non-Methyl HT-SELEX, 1 experiments median 0.949 0.917 0.927 0.888 0.869 0.833
best 0.949 0.917 0.927 0.888 0.869 0.833
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX4 {3.1.1.4} (TFClass)
TFClass IDTFClass: 3.1.1.4.1
HGNCHGNC:5105
MGIMGI:96176
EntrezGene (human)GeneID:3201
(SSTAR profile)
EntrezGene (mouse)GeneID:15401
(SSTAR profile)
UniProt ID (human)HXA4_HUMAN
UniProt ID (mouse)HXA4_MOUSE
UniProt AC (human)Q00056
(TFClass)
UniProt AC (mouse)P06798
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
012585.02337.02497.02143.0
021992.03814.01989.01767.0
032371.02436.04179.0576.0
04439.03497.0951.04675.0
0510.013.00.09539.0
069562.00.00.00.0
079562.00.00.00.0
080.0926.01.08635.0
0910.0106.06180.03266.0
107011.0163.02130.0258.0
111102.753193.752074.753190.75
121606.02922.02799.02235.0
PFM
ACGT
010.270.2440.2610.224
020.2080.3990.2080.185
030.2480.2550.4370.06
040.0460.3660.0990.489
050.0010.0010.00.998
061.00.00.00.0
071.00.00.00.0
080.00.0970.00.903
090.0010.0110.6460.342
100.7330.0170.2230.027
110.1150.3340.2170.334
120.1680.3060.2930.234
PWM
ACGT
010.078-0.0230.044-0.109
02-0.1820.467-0.184-0.302
03-0.0080.0190.558-1.42
04-1.6910.38-0.920.67
05-5.271-5.053-6.9511.383
061.386-6.951-6.951-6.951
071.386-6.951-6.951-6.951
08-6.951-0.947-6.5891.284
09-5.271-3.0950.9490.312
101.075-2.673-0.115-2.218
11-0.7730.289-0.1420.289
12-0.3970.2010.158-0.067
Standard thresholds
P-value Threshold
0.001 4.84506
0.0005 5.981265
0.0001 7.728405