MotifHXA2.H12CORE.0.SM.B
Gene (human)HOXA2
(GeneCards)
Gene synonyms (human)HOX1K
Gene (mouse)Hoxa2
Gene synonyms (mouse)Hox-1.11, Hoxa-2
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length13
ConsensusnvvYTAATTASvn
GC content39.0%
Information content (bits; total / per base)12.662 / 0.974
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words8198

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.986 0.976 0.975 0.961 0.934 0.92
best 0.995 0.991 0.991 0.985 0.98 0.971
Methyl HT-SELEX, 2 experiments median 0.992 0.986 0.985 0.977 0.967 0.955
best 0.994 0.99 0.989 0.982 0.968 0.956
Non-Methyl HT-SELEX, 6 experiments median 0.957 0.934 0.91 0.885 0.81 0.802
best 0.995 0.991 0.991 0.985 0.98 0.971
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX2 {3.1.1.2} (TFClass)
TFClass IDTFClass: 3.1.1.2.1
HGNCHGNC:5103
MGIMGI:96174
EntrezGene (human)GeneID:3199
(SSTAR profile)
EntrezGene (mouse)GeneID:15399
(SSTAR profile)
UniProt ID (human)HXA2_HUMAN
UniProt ID (mouse)HXA2_MOUSE
UniProt AC (human)O43364
(TFClass)
UniProt AC (mouse)P31245
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 6
Methyl-HT-SELEX 2
PCM
ACGT
011861.52557.51904.51874.5
021341.254106.251458.251292.25
032175.02721.02996.0306.0
04205.05450.0600.01943.0
050.00.00.08198.0
068198.00.00.00.0
078198.00.00.00.0
080.00.00.08198.0
090.092.01784.06322.0
107558.08.0612.020.0
11420.05246.01775.0757.0
121310.253297.252470.251120.25
131791.52737.51752.51916.5
PFM
ACGT
010.2270.3120.2320.229
020.1640.5010.1780.158
030.2650.3320.3650.037
040.0250.6650.0730.237
050.00.00.01.0
061.00.00.00.0
071.00.00.00.0
080.00.00.01.0
090.00.0110.2180.771
100.9220.0010.0750.002
110.0510.640.2170.092
120.160.4020.3010.137
130.2190.3340.2140.234
PWM
ACGT
01-0.0960.221-0.073-0.089
02-0.4230.694-0.34-0.461
030.0590.2830.379-1.896
04-2.2930.977-1.226-0.053
05-6.814-6.814-6.8141.385
061.385-6.814-6.814-6.814
071.385-6.814-6.814-6.814
08-6.814-6.814-6.8141.385
09-6.814-3.08-0.1391.126
101.304-5.299-1.206-4.524
11-1.5810.939-0.144-0.994
12-0.4470.4750.187-0.603
13-0.1340.289-0.156-0.067
Standard thresholds
P-value Threshold
0.001 2.43861
0.0005 4.55761
0.0001 7.564425