MotifHXA11.H12CORE.1.SM.B
Gene (human)HOXA11
(GeneCards)
Gene synonyms (human)HOX1I
Gene (mouse)Hoxa11
Gene synonyms (mouse)Hox-1.9, Hoxa-11
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length12
ConsensusnWTTTACGAYbh
GC content36.77%
Information content (bits; total / per base)13.702 / 1.142
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9577

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 2 (14) 0.779 0.827 0.666 0.722 0.697 0.752 2.049 2.139 24.959 61.319

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.938 0.922 0.826 0.81 0.701 0.706
best 0.989 0.986 0.899 0.894 0.75 0.764
Methyl HT-SELEX, 1 experiments median 0.973 0.965 0.865 0.855 0.73 0.738
best 0.973 0.965 0.865 0.855 0.73 0.738
Non-Methyl HT-SELEX, 3 experiments median 0.903 0.878 0.786 0.766 0.672 0.674
best 0.989 0.986 0.899 0.894 0.75 0.764
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX9-13 {3.1.1.8} (TFClass)
TFClass IDTFClass: 3.1.1.8.9
HGNCHGNC:5101
MGIMGI:96172
EntrezGene (human)GeneID:3207
(SSTAR profile)
EntrezGene (mouse)GeneID:15396
(SSTAR profile)
UniProt ID (human)HXA11_HUMAN
UniProt ID (mouse)HXA11_MOUSE
UniProt AC (human)P31270
(TFClass)
UniProt AC (mouse)P31311
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 2 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
013337.51665.52392.52181.5
021612.75976.751118.755868.75
03349.0109.0267.08852.0
0467.041.025.09444.0
051396.012.05.08164.0
069575.01.00.01.0
071.08949.07.0620.0
0824.05.09490.058.0
099327.061.0124.065.0
1060.06533.0962.02022.0
111331.04769.01636.01841.0
122262.01720.01387.04208.0
PFM
ACGT
010.3480.1740.250.228
020.1680.1020.1170.613
030.0360.0110.0280.924
040.0070.0040.0030.986
050.1460.0010.0010.852
061.00.00.00.0
070.00.9340.0010.065
080.0030.0010.9910.006
090.9740.0060.0130.007
100.0060.6820.10.211
110.1390.4980.1710.192
120.2360.180.1450.439
PWM
ACGT
010.332-0.363-0.001-0.093
02-0.395-0.895-0.760.896
03-1.92-3.07-2.1861.307
04-3.543-4.014-4.4751.372
05-0.539-5.122-5.7951.226
061.385-6.59-6.952-6.59
07-6.591.318-5.553-1.348
08-4.513-5.7951.376-3.683
091.359-3.634-2.943-3.573
10-3.651.003-0.91-0.169
11-0.5860.689-0.38-0.262
12-0.057-0.33-0.5450.564
Standard thresholds
P-value Threshold
0.001 2.73751
0.0005 4.10713
0.0001 6.877475