Motif | HXA11.H12CORE.1.SM.B |
Gene (human) | HOXA11 (GeneCards) |
Gene synonyms (human) | HOX1I |
Gene (mouse) | Hoxa11 |
Gene synonyms (mouse) | Hox-1.9, Hoxa-11 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif | HXA11.H12CORE.1.SM.B |
Gene (human) | HOXA11 (GeneCards) |
Gene synonyms (human) | HOX1I |
Gene (mouse) | Hoxa11 |
Gene synonyms (mouse) | Hox-1.9, Hoxa-11 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif length | 12 |
Consensus | nWTTTACGAYbh |
GC content | 36.77% |
Information content (bits; total / per base) | 13.702 / 1.142 |
Data sources | HT-SELEX + Methyl-HT-SELEX |
Aligned words | 9577 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Mouse | 2 (14) | 0.779 | 0.827 | 0.666 | 0.722 | 0.697 | 0.752 | 2.049 | 2.139 | 24.959 | 61.319 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 4 experiments | median | 0.938 | 0.922 | 0.826 | 0.81 | 0.701 | 0.706 |
best | 0.989 | 0.986 | 0.899 | 0.894 | 0.75 | 0.764 | |
Methyl HT-SELEX, 1 experiments | median | 0.973 | 0.965 | 0.865 | 0.855 | 0.73 | 0.738 |
best | 0.973 | 0.965 | 0.865 | 0.855 | 0.73 | 0.738 | |
Non-Methyl HT-SELEX, 3 experiments | median | 0.903 | 0.878 | 0.786 | 0.766 | 0.672 | 0.674 |
best | 0.989 | 0.986 | 0.899 | 0.894 | 0.75 | 0.764 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | HOX-related {3.1.1} (TFClass) |
TF subfamily | HOX9-13 {3.1.1.8} (TFClass) |
TFClass ID | TFClass: 3.1.1.8.9 |
HGNC | HGNC:5101 |
MGI | MGI:96172 |
EntrezGene (human) | GeneID:3207 (SSTAR profile) |
EntrezGene (mouse) | GeneID:15396 (SSTAR profile) |
UniProt ID (human) | HXA11_HUMAN |
UniProt ID (mouse) | HXA11_MOUSE |
UniProt AC (human) | P31270 (TFClass) |
UniProt AC (mouse) | P31311 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 2 mouse |
HT-SELEX | 3 |
Methyl-HT-SELEX | 1 |
PCM | HXA11.H12CORE.1.SM.B.pcm |
PWM | HXA11.H12CORE.1.SM.B.pwm |
PFM | HXA11.H12CORE.1.SM.B.pfm |
Alignment | HXA11.H12CORE.1.SM.B.words.tsv |
Threshold to P-value map | HXA11.H12CORE.1.SM.B.thr |
Motif in other formats | |
JASPAR format | HXA11.H12CORE.1.SM.B_jaspar_format.txt |
MEME format | HXA11.H12CORE.1.SM.B_meme_format.meme |
Transfac format | HXA11.H12CORE.1.SM.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 3337.5 | 1665.5 | 2392.5 | 2181.5 |
02 | 1612.75 | 976.75 | 1118.75 | 5868.75 |
03 | 349.0 | 109.0 | 267.0 | 8852.0 |
04 | 67.0 | 41.0 | 25.0 | 9444.0 |
05 | 1396.0 | 12.0 | 5.0 | 8164.0 |
06 | 9575.0 | 1.0 | 0.0 | 1.0 |
07 | 1.0 | 8949.0 | 7.0 | 620.0 |
08 | 24.0 | 5.0 | 9490.0 | 58.0 |
09 | 9327.0 | 61.0 | 124.0 | 65.0 |
10 | 60.0 | 6533.0 | 962.0 | 2022.0 |
11 | 1331.0 | 4769.0 | 1636.0 | 1841.0 |
12 | 2262.0 | 1720.0 | 1387.0 | 4208.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.348 | 0.174 | 0.25 | 0.228 |
02 | 0.168 | 0.102 | 0.117 | 0.613 |
03 | 0.036 | 0.011 | 0.028 | 0.924 |
04 | 0.007 | 0.004 | 0.003 | 0.986 |
05 | 0.146 | 0.001 | 0.001 | 0.852 |
06 | 1.0 | 0.0 | 0.0 | 0.0 |
07 | 0.0 | 0.934 | 0.001 | 0.065 |
08 | 0.003 | 0.001 | 0.991 | 0.006 |
09 | 0.974 | 0.006 | 0.013 | 0.007 |
10 | 0.006 | 0.682 | 0.1 | 0.211 |
11 | 0.139 | 0.498 | 0.171 | 0.192 |
12 | 0.236 | 0.18 | 0.145 | 0.439 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.332 | -0.363 | -0.001 | -0.093 |
02 | -0.395 | -0.895 | -0.76 | 0.896 |
03 | -1.92 | -3.07 | -2.186 | 1.307 |
04 | -3.543 | -4.014 | -4.475 | 1.372 |
05 | -0.539 | -5.122 | -5.795 | 1.226 |
06 | 1.385 | -6.59 | -6.952 | -6.59 |
07 | -6.59 | 1.318 | -5.553 | -1.348 |
08 | -4.513 | -5.795 | 1.376 | -3.683 |
09 | 1.359 | -3.634 | -2.943 | -3.573 |
10 | -3.65 | 1.003 | -0.91 | -0.169 |
11 | -0.586 | 0.689 | -0.38 | -0.262 |
12 | -0.057 | -0.33 | -0.545 | 0.564 |
P-value | Threshold |
---|---|
0.001 | 2.73751 |
0.0005 | 4.10713 |
0.0001 | 6.877475 |