Motif | HXA11.H12CORE.0.PS.A |
Gene (human) | HOXA11 (GeneCards) |
Gene synonyms (human) | HOX1I |
Gene (mouse) | Hoxa11 |
Gene synonyms (mouse) | Hox-1.9, Hoxa-11 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | A |
Motif | HXA11.H12CORE.0.PS.A |
Gene (human) | HOXA11 (GeneCards) |
Gene synonyms (human) | HOX1I |
Gene (mouse) | Hoxa11 |
Gene synonyms (mouse) | Hox-1.9, Hoxa-11 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | A |
Motif length | 14 |
Consensus | WTTTATKRbbhbhh |
GC content | 31.9% |
Information content (bits; total / per base) | 11.213 / 0.801 |
Data sources | ChIP-Seq + HT-SELEX |
Aligned words | 980 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Mouse | 2 (14) | 0.796 | 0.852 | 0.679 | 0.729 | 0.768 | 0.851 | 2.5 | 2.893 | 33.959 | 83.796 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 4 experiments | median | 0.858 | 0.803 | 0.767 | 0.727 | 0.652 | 0.648 |
best | 0.909 | 0.864 | 0.824 | 0.787 | 0.68 | 0.686 | |
Methyl HT-SELEX, 1 experiments | median | 0.853 | 0.792 | 0.766 | 0.723 | 0.648 | 0.645 |
best | 0.853 | 0.792 | 0.766 | 0.723 | 0.648 | 0.645 | |
Non-Methyl HT-SELEX, 3 experiments | median | 0.863 | 0.814 | 0.768 | 0.732 | 0.655 | 0.652 |
best | 0.909 | 0.864 | 0.824 | 0.787 | 0.68 | 0.686 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | HOX-related {3.1.1} (TFClass) |
TF subfamily | HOX9-13 {3.1.1.8} (TFClass) |
TFClass ID | TFClass: 3.1.1.8.9 |
HGNC | HGNC:5101 |
MGI | MGI:96172 |
EntrezGene (human) | GeneID:3207 (SSTAR profile) |
EntrezGene (mouse) | GeneID:15396 (SSTAR profile) |
UniProt ID (human) | HXA11_HUMAN |
UniProt ID (mouse) | HXA11_MOUSE |
UniProt AC (human) | P31270 (TFClass) |
UniProt AC (mouse) | P31311 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 2 mouse |
HT-SELEX | 3 |
Methyl-HT-SELEX | 1 |
PCM | HXA11.H12CORE.0.PS.A.pcm |
PWM | HXA11.H12CORE.0.PS.A.pwm |
PFM | HXA11.H12CORE.0.PS.A.pfm |
Alignment | HXA11.H12CORE.0.PS.A.words.tsv |
Threshold to P-value map | HXA11.H12CORE.0.PS.A.thr |
Motif in other formats | |
JASPAR format | HXA11.H12CORE.0.PS.A_jaspar_format.txt |
MEME format | HXA11.H12CORE.0.PS.A_meme_format.meme |
Transfac format | HXA11.H12CORE.0.PS.A_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 98.0 | 64.0 | 76.0 | 742.0 |
02 | 3.0 | 10.0 | 7.0 | 960.0 |
03 | 3.0 | 6.0 | 4.0 | 967.0 |
04 | 204.0 | 17.0 | 21.0 | 738.0 |
05 | 935.0 | 30.0 | 8.0 | 7.0 |
06 | 11.0 | 54.0 | 43.0 | 872.0 |
07 | 82.0 | 10.0 | 639.0 | 249.0 |
08 | 398.0 | 21.0 | 494.0 | 67.0 |
09 | 23.0 | 457.0 | 342.0 | 158.0 |
10 | 96.0 | 416.0 | 157.0 | 311.0 |
11 | 144.0 | 229.0 | 68.0 | 539.0 |
12 | 146.0 | 195.0 | 276.0 | 363.0 |
13 | 181.0 | 252.0 | 144.0 | 403.0 |
14 | 178.0 | 209.0 | 127.0 | 466.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.1 | 0.065 | 0.078 | 0.757 |
02 | 0.003 | 0.01 | 0.007 | 0.98 |
03 | 0.003 | 0.006 | 0.004 | 0.987 |
04 | 0.208 | 0.017 | 0.021 | 0.753 |
05 | 0.954 | 0.031 | 0.008 | 0.007 |
06 | 0.011 | 0.055 | 0.044 | 0.89 |
07 | 0.084 | 0.01 | 0.652 | 0.254 |
08 | 0.406 | 0.021 | 0.504 | 0.068 |
09 | 0.023 | 0.466 | 0.349 | 0.161 |
10 | 0.098 | 0.424 | 0.16 | 0.317 |
11 | 0.147 | 0.234 | 0.069 | 0.55 |
12 | 0.149 | 0.199 | 0.282 | 0.37 |
13 | 0.185 | 0.257 | 0.147 | 0.411 |
14 | 0.182 | 0.213 | 0.13 | 0.476 |
A | C | G | T | |
---|---|---|---|---|
01 | -0.906 | -1.323 | -1.155 | 1.103 |
02 | -3.956 | -3.047 | -3.342 | 1.36 |
03 | -3.956 | -3.464 | -3.764 | 1.368 |
04 | -0.182 | -2.579 | -2.385 | 1.098 |
05 | 1.334 | -2.051 | -3.234 | -3.342 |
06 | -2.965 | -1.488 | -1.708 | 1.265 |
07 | -1.081 | -3.047 | 0.954 | 0.016 |
08 | 0.483 | -2.385 | 0.698 | -1.278 |
09 | -2.301 | 0.62 | 0.332 | -0.435 |
10 | -0.926 | 0.527 | -0.441 | 0.237 |
11 | -0.527 | -0.067 | -1.264 | 0.785 |
12 | -0.513 | -0.226 | 0.118 | 0.391 |
13 | -0.3 | 0.028 | -0.527 | 0.495 |
14 | -0.317 | -0.158 | -0.651 | 0.64 |
P-value | Threshold |
---|---|
0.001 | 4.41666 |
0.0005 | 5.37766 |
0.0001 | 7.31341 |