MotifHXA11.H12CORE.0.PS.A
Gene (human)HOXA11
(GeneCards)
Gene synonyms (human)HOX1I
Gene (mouse)Hoxa11
Gene synonyms (mouse)Hox-1.9, Hoxa-11
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length14
ConsensusWTTTATKRbbhbhh
GC content31.9%
Information content (bits; total / per base)11.213 / 0.801
Data sourcesChIP-Seq + HT-SELEX
Aligned words980

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 2 (14) 0.796 0.852 0.679 0.729 0.768 0.851 2.5 2.893 33.959 83.796

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.858 0.803 0.767 0.727 0.652 0.648
best 0.909 0.864 0.824 0.787 0.68 0.686
Methyl HT-SELEX, 1 experiments median 0.853 0.792 0.766 0.723 0.648 0.645
best 0.853 0.792 0.766 0.723 0.648 0.645
Non-Methyl HT-SELEX, 3 experiments median 0.863 0.814 0.768 0.732 0.655 0.652
best 0.909 0.864 0.824 0.787 0.68 0.686
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX9-13 {3.1.1.8} (TFClass)
TFClass IDTFClass: 3.1.1.8.9
HGNCHGNC:5101
MGIMGI:96172
EntrezGene (human)GeneID:3207
(SSTAR profile)
EntrezGene (mouse)GeneID:15396
(SSTAR profile)
UniProt ID (human)HXA11_HUMAN
UniProt ID (mouse)HXA11_MOUSE
UniProt AC (human)P31270
(TFClass)
UniProt AC (mouse)P31311
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 2 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
0198.064.076.0742.0
023.010.07.0960.0
033.06.04.0967.0
04204.017.021.0738.0
05935.030.08.07.0
0611.054.043.0872.0
0782.010.0639.0249.0
08398.021.0494.067.0
0923.0457.0342.0158.0
1096.0416.0157.0311.0
11144.0229.068.0539.0
12146.0195.0276.0363.0
13181.0252.0144.0403.0
14178.0209.0127.0466.0
PFM
ACGT
010.10.0650.0780.757
020.0030.010.0070.98
030.0030.0060.0040.987
040.2080.0170.0210.753
050.9540.0310.0080.007
060.0110.0550.0440.89
070.0840.010.6520.254
080.4060.0210.5040.068
090.0230.4660.3490.161
100.0980.4240.160.317
110.1470.2340.0690.55
120.1490.1990.2820.37
130.1850.2570.1470.411
140.1820.2130.130.476
PWM
ACGT
01-0.906-1.323-1.1551.103
02-3.956-3.047-3.3421.36
03-3.956-3.464-3.7641.368
04-0.182-2.579-2.3851.098
051.334-2.051-3.234-3.342
06-2.965-1.488-1.7081.265
07-1.081-3.0470.9540.016
080.483-2.3850.698-1.278
09-2.3010.620.332-0.435
10-0.9260.527-0.4410.237
11-0.527-0.067-1.2640.785
12-0.513-0.2260.1180.391
13-0.30.028-0.5270.495
14-0.317-0.158-0.6510.64
Standard thresholds
P-value Threshold
0.001 4.41666
0.0005 5.37766
0.0001 7.31341