MotifHXA10.H12INVIVO.1.M.D
Gene (human)HOXA10
(GeneCards)
Gene synonyms (human)HOX1H
Gene (mouse)Hoxa10
Gene synonyms (mouse)Hox-1.8, Hoxa-10
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
D
Motif length11
ConsensusdTTTACGAYbn
GC content36.97%
Information content (bits; total / per base)12.085 / 1.099
Data sourcesMethyl-HT-SELEX
Aligned words2176

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.958 0.936 0.893 0.866 0.798 0.778
best 0.998 0.996 0.989 0.986 0.902 0.892
Methyl HT-SELEX, 3 experiments median 0.977 0.964 0.935 0.914 0.846 0.828
best 0.998 0.996 0.989 0.986 0.889 0.892
Non-Methyl HT-SELEX, 5 experiments median 0.9 0.869 0.803 0.772 0.703 0.69
best 0.994 0.99 0.975 0.968 0.902 0.892
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX9-13 {3.1.1.8} (TFClass)
TFClass IDTFClass: 3.1.1.8.5
HGNCHGNC:5100
MGIMGI:96171
EntrezGene (human)GeneID:3206
(SSTAR profile)
EntrezGene (mouse)GeneID:15395
(SSTAR profile)
UniProt ID (human)HXA10_HUMAN
UniProt ID (mouse)HXA10_MOUSE
UniProt AC (human)P31260
(TFClass)
UniProt AC (mouse)P31310
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 5
Methyl-HT-SELEX 3
PCM
ACGT
01465.0382.0397.0932.0
02234.528.5123.51789.5
0324.08.05.02139.0
04842.06.00.01328.0
052176.00.00.00.0
061.01793.00.0382.0
070.04.02148.024.0
082140.05.028.03.0
095.01335.0217.0619.0
10305.0960.0543.0368.0
11488.25534.25332.25821.25
PFM
ACGT
010.2140.1760.1820.428
020.1080.0130.0570.822
030.0110.0040.0020.983
040.3870.0030.00.61
051.00.00.00.0
060.00.8240.00.176
070.00.0020.9870.011
080.9830.0020.0130.001
090.0020.6140.10.284
100.140.4410.250.169
110.2240.2460.1530.377
PWM
ACGT
01-0.156-0.352-0.3140.537
02-0.837-2.887-1.4711.188
03-3.047-4.008-4.3681.367
040.436-4.233-5.6490.89
051.384-5.649-5.649-5.649
06-5.231.19-5.649-0.352
07-5.649-4.5241.371-3.047
081.367-4.368-2.904-4.709
09-4.3680.896-0.9140.129
10-0.5760.566-0.002-0.389
11-0.108-0.018-0.4910.411
Standard thresholds
P-value Threshold
0.001 3.5245
0.0005 4.857075
0.0001 7.61619