MotifHXA10.H12INVITRO.0.S.B
Gene (human)HOXA10
(GeneCards)
Gene synonyms (human)HOX1H
Gene (mouse)Hoxa10
Gene synonyms (mouse)Hox-1.8, Hoxa-10
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length10
ConsensusdTTWATGRbn
GC content30.27%
Information content (bits; total / per base)9.886 / 0.989
Data sourcesHT-SELEX
Aligned words8657

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.942 0.905 0.918 0.877 0.836 0.806
best 0.987 0.976 0.982 0.969 0.949 0.933
Methyl HT-SELEX, 3 experiments median 0.956 0.926 0.938 0.902 0.869 0.838
best 0.987 0.976 0.982 0.969 0.905 0.9
Non-Methyl HT-SELEX, 5 experiments median 0.929 0.885 0.869 0.83 0.747 0.735
best 0.986 0.976 0.978 0.965 0.949 0.933
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX9-13 {3.1.1.8} (TFClass)
TFClass IDTFClass: 3.1.1.8.5
HGNCHGNC:5100
MGIMGI:96171
EntrezGene (human)GeneID:3206
(SSTAR profile)
EntrezGene (mouse)GeneID:15395
(SSTAR profile)
UniProt ID (human)HXA10_HUMAN
UniProt ID (mouse)HXA10_MOUSE
UniProt AC (human)P31260
(TFClass)
UniProt AC (mouse)P31310
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 5
Methyl-HT-SELEX 3
PCM
ACGT
011875.51343.51504.53933.5
02462.75144.75520.757528.75
034.02.044.08607.0
043938.02.035.04682.0
058626.00.031.00.0
060.02246.01.06410.0
070.044.06418.02195.0
085948.059.02350.0300.0
09353.254581.252068.251654.25
101890.752656.752155.751953.75
PFM
ACGT
010.2170.1550.1740.454
020.0530.0170.060.87
030.00.00.0050.994
040.4550.00.0040.541
050.9960.00.0040.0
060.00.2590.00.74
070.00.0050.7410.254
080.6870.0070.2710.035
090.0410.5290.2390.191
100.2180.3070.2490.226
PWM
ACGT
01-0.143-0.476-0.3630.597
02-1.539-2.69-1.4211.246
03-5.846-6.23-3.8461.38
040.598-6.23-4.0630.771
051.382-6.863-4.176-6.863
06-6.8630.037-6.4971.085
07-6.863-3.8461.0860.014
081.01-3.5660.082-1.97
09-1.8070.749-0.045-0.268
10-0.1350.205-0.004-0.102
Standard thresholds
P-value Threshold
0.001 4.891895
0.0005 6.069995
0.0001 7.507925