| Motif | HXA1.H12RSNP.0.SM.D |
| Gene (human) | HOXA1 (GeneCards) |
| Gene synonyms (human) | HOX1F |
| Gene (mouse) | Hoxa1 |
| Gene synonyms (mouse) | Era-1, Hox-1.6, Hoxa-1 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | D |
| Motif | HXA1.H12RSNP.0.SM.D |
| Gene (human) | HOXA1 (GeneCards) |
| Gene synonyms (human) | HOX1F |
| Gene (mouse) | Hoxa1 |
| Gene synonyms (mouse) | Era-1, Hox-1.6, Hoxa-1 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | D |
| Motif length | 12 |
| Consensus | nnSbTAATKAbn |
| GC content | 36.13% |
| Information content (bits; total / per base) | 10.859 / 0.905 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 9142 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.936 | 0.907 | 0.872 | 0.846 | 0.778 | 0.768 |
| best | 0.979 | 0.967 | 0.964 | 0.945 | 0.935 | 0.91 | |
| Methyl HT-SELEX, 1 experiments | median | 0.971 | 0.953 | 0.95 | 0.925 | 0.89 | 0.866 |
| best | 0.971 | 0.953 | 0.95 | 0.925 | 0.89 | 0.866 | |
| Non-Methyl HT-SELEX, 3 experiments | median | 0.902 | 0.861 | 0.794 | 0.766 | 0.667 | 0.671 |
| best | 0.979 | 0.967 | 0.964 | 0.945 | 0.935 | 0.91 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | HOX-related {3.1.1} (TFClass) |
| TF subfamily | HOX1 {3.1.1.1} (TFClass) |
| TFClass ID | TFClass: 3.1.1.1.1 |
| HGNC | HGNC:5099 |
| MGI | MGI:96170 |
| EntrezGene (human) | GeneID:3198 (SSTAR profile) |
| EntrezGene (mouse) | |
| UniProt ID (human) | HXA1_HUMAN |
| UniProt ID (mouse) | HXA1_MOUSE |
| UniProt AC (human) | P49639 (TFClass) |
| UniProt AC (mouse) | P09022 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 3 |
| Methyl-HT-SELEX | 1 |
| PCM | HXA1.H12RSNP.0.SM.D.pcm |
| PWM | HXA1.H12RSNP.0.SM.D.pwm |
| PFM | HXA1.H12RSNP.0.SM.D.pfm |
| Alignment | HXA1.H12RSNP.0.SM.D.words.tsv |
| Threshold to P-value map | HXA1.H12RSNP.0.SM.D.thr |
| Motif in other formats | |
| JASPAR format | HXA1.H12RSNP.0.SM.D_jaspar_format.txt |
| MEME format | HXA1.H12RSNP.0.SM.D_meme_format.meme |
| Transfac format | HXA1.H12RSNP.0.SM.D_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 2020.25 | 1818.25 | 2455.25 | 2848.25 |
| 02 | 2000.5 | 3430.5 | 2352.5 | 1358.5 |
| 03 | 1520.0 | 2760.0 | 4655.0 | 207.0 |
| 04 | 183.0 | 3680.0 | 1954.0 | 3325.0 |
| 05 | 0.0 | 0.0 | 0.0 | 9142.0 |
| 06 | 9142.0 | 0.0 | 0.0 | 0.0 |
| 07 | 9142.0 | 0.0 | 0.0 | 0.0 |
| 08 | 0.0 | 220.0 | 0.0 | 8922.0 |
| 09 | 1.0 | 1017.0 | 2606.0 | 5518.0 |
| 10 | 7605.0 | 5.0 | 1522.0 | 10.0 |
| 11 | 1042.75 | 3315.75 | 2706.75 | 2076.75 |
| 12 | 1832.0 | 2742.0 | 2392.0 | 2176.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.221 | 0.199 | 0.269 | 0.312 |
| 02 | 0.219 | 0.375 | 0.257 | 0.149 |
| 03 | 0.166 | 0.302 | 0.509 | 0.023 |
| 04 | 0.02 | 0.403 | 0.214 | 0.364 |
| 05 | 0.0 | 0.0 | 0.0 | 1.0 |
| 06 | 1.0 | 0.0 | 0.0 | 0.0 |
| 07 | 1.0 | 0.0 | 0.0 | 0.0 |
| 08 | 0.0 | 0.024 | 0.0 | 0.976 |
| 09 | 0.0 | 0.111 | 0.285 | 0.604 |
| 10 | 0.832 | 0.001 | 0.166 | 0.001 |
| 11 | 0.114 | 0.363 | 0.296 | 0.227 |
| 12 | 0.2 | 0.3 | 0.262 | 0.238 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.123 | -0.228 | 0.072 | 0.22 |
| 02 | -0.133 | 0.406 | 0.029 | -0.52 |
| 03 | -0.407 | 0.188 | 0.711 | -2.392 |
| 04 | -2.513 | 0.476 | -0.157 | 0.375 |
| 05 | -6.911 | -6.911 | -6.911 | 1.386 |
| 06 | 1.386 | -6.911 | -6.911 | -6.911 |
| 07 | 1.386 | -6.911 | -6.911 | -6.911 |
| 08 | -6.911 | -2.331 | -6.911 | 1.361 |
| 09 | -6.547 | -0.808 | 0.131 | 0.881 |
| 10 | 1.202 | -5.75 | -0.406 | -5.227 |
| 11 | -0.784 | 0.372 | 0.169 | -0.096 |
| 12 | -0.221 | 0.182 | 0.046 | -0.049 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.310365 |
| 0.0005 | 5.909725 |
| 0.0001 | 7.820925 |