MotifHXA1.H12CORE.1.S.B
Gene (human)HOXA1
(GeneCards)
Gene synonyms (human)HOX1F
Gene (mouse)Hoxa1
Gene synonyms (mouse)Era-1, Hox-1.6, Hoxa-1
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length17
ConsensushWWWdhvvbTAATTAvn
GC content25.16%
Information content (bits; total / per base)14.836 / 0.873
Data sourcesHT-SELEX
Aligned words1696

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.935 0.908 0.86 0.836 0.76 0.753
best 0.969 0.95 0.952 0.926 0.922 0.891
Methyl HT-SELEX, 1 experiments median 0.964 0.942 0.94 0.911 0.865 0.842
best 0.964 0.942 0.94 0.911 0.865 0.842
Non-Methyl HT-SELEX, 3 experiments median 0.906 0.873 0.779 0.761 0.654 0.665
best 0.969 0.95 0.952 0.926 0.922 0.891
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX1 {3.1.1.1} (TFClass)
TFClass IDTFClass: 3.1.1.1.1
HGNCHGNC:5099
MGIMGI:96170
EntrezGene (human)GeneID:3198
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)HXA1_HUMAN
UniProt ID (mouse)HXA1_MOUSE
UniProt AC (human)P49639
(TFClass)
UniProt AC (mouse)P09022
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01665.5229.5187.5613.5
02436.25120.2576.251063.25
03795.068.0144.0689.0
041064.082.0158.0392.0
05487.0135.0172.0902.0
06331.0358.0313.0694.0
07793.0334.0329.0240.0
08363.0598.0652.083.0
0942.0728.0408.0518.0
100.02.00.01694.0
111693.00.03.00.0
121696.00.00.00.0
130.00.00.01696.0
140.029.06.01661.0
151608.00.088.00.0
16432.75639.75556.7566.75
17396.25530.25306.25463.25
PFM
ACGT
010.3920.1350.1110.362
020.2570.0710.0450.627
030.4690.040.0850.406
040.6270.0480.0930.231
050.2870.080.1010.532
060.1950.2110.1850.409
070.4680.1970.1940.142
080.2140.3530.3840.049
090.0250.4290.2410.305
100.00.0010.00.999
110.9980.00.0020.0
121.00.00.00.0
130.00.00.01.0
140.00.0170.0040.979
150.9480.00.0520.0
160.2550.3770.3280.039
170.2340.3130.1810.273
PWM
ACGT
010.449-0.61-0.810.368
020.028-1.249-1.6960.917
030.627-1.808-1.0710.484
040.917-1.625-0.98-0.078
050.138-1.135-0.8960.753
06-0.246-0.168-0.3020.491
070.624-0.237-0.252-0.566
08-0.1550.3430.429-1.613
09-2.2730.539-0.0380.199
10-5.434-4.704-5.4341.382
111.381-5.434-4.473-5.434
121.383-5.434-5.434-5.434
13-5.434-5.434-5.4341.383
14-5.434-2.625-3.9921.362
151.33-5.434-1.556-5.434
160.020.410.271-1.826
17-0.0670.223-0.3240.088
Standard thresholds
P-value Threshold
0.001 1.84371
0.0005 3.29191
0.0001 6.54726