MotifHXA1.H12CORE.0.SM.B
Gene (human)HOXA1
(GeneCards)
Gene synonyms (human)HOX1F
Gene (mouse)Hoxa1
Gene synonyms (mouse)Era-1, Hox-1.6, Hoxa-1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length12
ConsensusnnSbTAATKAbn
GC content36.13%
Information content (bits; total / per base)10.859 / 0.905
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9142

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.936 0.907 0.872 0.846 0.778 0.768
best 0.979 0.967 0.964 0.945 0.935 0.91
Methyl HT-SELEX, 1 experiments median 0.971 0.953 0.95 0.925 0.89 0.866
best 0.971 0.953 0.95 0.925 0.89 0.866
Non-Methyl HT-SELEX, 3 experiments median 0.902 0.861 0.794 0.766 0.667 0.671
best 0.979 0.967 0.964 0.945 0.935 0.91
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHOX-related {3.1.1} (TFClass)
TF subfamilyHOX1 {3.1.1.1} (TFClass)
TFClass IDTFClass: 3.1.1.1.1
HGNCHGNC:5099
MGIMGI:96170
EntrezGene (human)GeneID:3198
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)HXA1_HUMAN
UniProt ID (mouse)HXA1_MOUSE
UniProt AC (human)P49639
(TFClass)
UniProt AC (mouse)P09022
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
012020.251818.252455.252848.25
022000.53430.52352.51358.5
031520.02760.04655.0207.0
04183.03680.01954.03325.0
050.00.00.09142.0
069142.00.00.00.0
079142.00.00.00.0
080.0220.00.08922.0
091.01017.02606.05518.0
107605.05.01522.010.0
111042.753315.752706.752076.75
121832.02742.02392.02176.0
PFM
ACGT
010.2210.1990.2690.312
020.2190.3750.2570.149
030.1660.3020.5090.023
040.020.4030.2140.364
050.00.00.01.0
061.00.00.00.0
071.00.00.00.0
080.00.0240.00.976
090.00.1110.2850.604
100.8320.0010.1660.001
110.1140.3630.2960.227
120.20.30.2620.238
PWM
ACGT
01-0.123-0.2280.0720.22
02-0.1330.4060.029-0.52
03-0.4070.1880.711-2.392
04-2.5130.476-0.1570.375
05-6.911-6.911-6.9111.386
061.386-6.911-6.911-6.911
071.386-6.911-6.911-6.911
08-6.911-2.331-6.9111.361
09-6.547-0.8080.1310.881
101.202-5.75-0.406-5.227
11-0.7840.3720.169-0.096
12-0.2210.1820.046-0.049
Standard thresholds
P-value Threshold
0.001 4.310365
0.0005 5.909725
0.0001 7.820925