HSFY1.H12CORE.1.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	HSFY1.H12CORE.1.S.B
Gene (human)	HSFY1 (GeneCards)
Gene synonyms (human)	HSFY2, HSF2L, HSFY, HSF2L, HSFY
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	18
Consensus	nSRTTCGAAhSRTTCKWh
GC content	44.69%
Information content (bits; total / per base)	18.247 / 1.014
Data sources	HT-SELEX
Aligned words	9984

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.942	0.942	0.773	0.789	0.64	0.679
Overall, 6 experiments	best	1.0	1.0	0.996	0.996	0.829	0.856
Methyl HT-SELEX, 2 experiments	median	0.878	0.882	0.673	0.705	0.574	0.614
Methyl HT-SELEX, 2 experiments	best	0.911	0.917	0.68	0.722	0.578	0.62
Non-Methyl HT-SELEX, 4 experiments	median	0.986	0.983	0.878	0.879	0.714	0.741
Non-Methyl HT-SELEX, 4 experiments	best	1.0	1.0	0.996	0.996	0.829	0.856

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Heat shock factors {3.4} (TFClass)
TF family	HSF {3.4.1} (TFClass)
TF subfamily	{3.4.1.0} (TFClass)
TFClass ID	TFClass: 3.4.1.0.8
HGNC	HGNC:18568 HGNC:23950
MGI
EntrezGene (human)	GeneID:159119 (SSTAR profile) GeneID:86614 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	HSFY1_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q96LI6 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	4
Methyl-HT-SELEX	2

PCM	HSFY1.H12CORE.1.S.B.pcm
PWM	HSFY1.H12CORE.1.S.B.pwm
PFM	HSFY1.H12CORE.1.S.B.pfm
Alignment	HSFY1.H12CORE.1.S.B.words.tsv
Threshold to P-value map	HSFY1.H12CORE.1.S.B.thr
Motif in other formats
JASPAR format	HSFY1.H12CORE.1.S.B_jaspar_format.txt
MEME format	HSFY1.H12CORE.1.S.B_meme_format.meme
Transfac format	HSFY1.H12CORE.1.S.B_transfac_format.txt
Homer format	HSFY1.H12CORE.1.S.B_homer_format_0.001.txt HSFY1.H12CORE.1.S.B_homer_format_0.0005.txt HSFY1.H12CORE.1.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2962.25	2005.25	3481.25	1535.25
02	1006.75	6818.75	1450.75	707.75
03	3584.0	457.0	5857.0	86.0
04	154.0	225.0	51.0	9554.0
05	68.0	15.0	17.0	9884.0
06	11.0	9950.0	18.0	5.0
07	12.0	520.0	8827.0	625.0
08	9477.0	54.0	113.0	340.0
09	7962.0	198.0	62.0	1762.0
10	4819.0	1353.0	1010.0	2802.0
11	940.0	6435.0	1830.0	779.0
12	2996.0	349.0	6245.0	394.0
13	325.0	583.0	310.0	8766.0
14	309.0	418.0	306.0	8951.0
15	161.0	9148.0	482.0	193.0
16	442.0	1413.0	6269.0	1860.0
17	7394.5	672.5	667.5	1249.5
18	4142.5	1912.5	796.5	3132.5

PFM

	A	C	G	T
01	0.297	0.201	0.349	0.154
02	0.101	0.683	0.145	0.071
03	0.359	0.046	0.587	0.009
04	0.015	0.023	0.005	0.957
05	0.007	0.002	0.002	0.99
06	0.001	0.997	0.002	0.001
07	0.001	0.052	0.884	0.063
08	0.949	0.005	0.011	0.034
09	0.797	0.02	0.006	0.176
10	0.483	0.136	0.101	0.281
11	0.094	0.645	0.183	0.078
12	0.3	0.035	0.626	0.039
13	0.033	0.058	0.031	0.878
14	0.031	0.042	0.031	0.897
15	0.016	0.916	0.048	0.019
16	0.044	0.142	0.628	0.186
17	0.741	0.067	0.067	0.125
18	0.415	0.192	0.08	0.314

PWM

	A	C	G	T
01	0.171	-0.219	0.332	-0.485
02	-0.907	1.004	-0.542	-1.258
03	0.362	-1.694	0.852	-3.343
04	-2.772	-2.397	-3.847	1.342
05	-3.571	-4.973	-4.863	1.376
06	-5.235	1.382	-4.813	-5.835
07	-5.163	-1.565	1.262	-1.382
08	1.333	-3.793	-3.076	-1.988
09	1.159	-2.524	-3.66	-0.348
10	0.657	-0.612	-0.903	0.116
11	-0.975	0.946	-0.31	-1.162
12	0.182	-1.962	0.917	-1.841
13	-2.032	-1.451	-2.079	1.256
14	-2.083	-1.782	-2.092	1.276
15	-2.728	1.298	-1.641	-2.549
16	-1.727	-0.568	0.92	-0.294
17	1.085	-1.309	-1.316	-0.691
18	0.506	-0.266	-1.14	0.227

Standard thresholds

P-value	Threshold
0.001	1.20341
0.0005	2.57016
0.0001	5.43211