MotifHSF5.H12INVITRO.1.S.C
Gene (human)HSF5
(GeneCards)
Gene synonyms (human)HSTF5
Gene (mouse)Hsf5
Gene synonyms (mouse)Gm739
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
C
Motif length12
ConsensusnbhRCGTTCbRh
GC content46.94%
Information content (bits; total / per base)11.767 / 0.981
Data sourcesHT-SELEX
Aligned words8968

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.981 0.97 0.942 0.927 0.852 0.846
best 0.987 0.978 0.976 0.963 0.936 0.919
Methyl HT-SELEX, 1 experiments median 0.987 0.978 0.976 0.963 0.936 0.919
best 0.987 0.978 0.976 0.963 0.936 0.919
Non-Methyl HT-SELEX, 1 experiments median 0.975 0.962 0.908 0.891 0.768 0.772
best 0.975 0.962 0.908 0.891 0.768 0.772

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.747 0.421 0.747 0.612
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHeat shock factors {3.4} (TFClass)
TF familyHSF {3.4.1} (TFClass)
TF subfamily {3.4.1.0} (TFClass)
TFClass IDTFClass: 3.4.1.0.5
HGNCHGNC:26862
MGIMGI:2685585
EntrezGene (human)GeneID:124535
(SSTAR profile)
EntrezGene (mouse)GeneID:327992
(SSTAR profile)
UniProt ID (human)HSF5_HUMAN
UniProt ID (mouse)HSF5_MOUSE
UniProt AC (human)Q4G112
(TFClass)
UniProt AC (mouse)Q5ND04
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
011689.52726.52196.52355.5
021011.253495.252115.252346.25
034629.01789.0835.01715.0
046658.0269.01810.0231.0
0554.08657.069.0188.0
061759.09.07200.00.0
070.01.00.08967.0
080.00.00.08968.0
095.08962.01.00.0
1017.03220.02590.03141.0
117036.5445.51097.5388.5
123140.751756.751271.752798.75
PFM
ACGT
010.1880.3040.2450.263
020.1130.390.2360.262
030.5160.1990.0930.191
040.7420.030.2020.026
050.0060.9650.0080.021
060.1960.0010.8030.0
070.00.00.01.0
080.00.00.01.0
090.0010.9990.00.0
100.0020.3590.2890.35
110.7850.050.1220.043
120.350.1960.1420.312
PWM
ACGT
01-0.2830.195-0.020.049
02-0.7950.444-0.0580.045
030.724-0.225-0.986-0.268
041.088-2.113-0.214-2.264
05-3.6861.35-3.45-2.468
06-0.242-5.2941.166-6.894
07-6.894-6.53-6.8941.385
08-6.894-6.894-6.8941.386
09-5.7321.385-6.53-6.894
10-4.7570.3620.1440.337
111.143-1.612-0.713-1.748
120.337-0.244-0.5660.222
Standard thresholds
P-value Threshold
0.001 3.83998
0.0005 5.264665
0.0001 7.594505