MotifHSF4.H12INVIVO.0.SM.D
Gene (human)HSF4
(GeneCards)
Gene synonyms (human)
Gene (mouse)Hsf4
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length19
ConsensusnvbRGAAbvTTCTAGAWbn
GC content43.3%
Information content (bits; total / per base)17.859 / 0.94
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words2317

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.999 0.999 0.997 0.996 0.983 0.98
best 1.0 1.0 1.0 1.0 0.999 0.999
Methyl HT-SELEX, 1 experiments median 0.999 0.998 0.996 0.994 0.969 0.965
best 0.999 0.998 0.996 0.994 0.969 0.965
Non-Methyl HT-SELEX, 3 experiments median 1.0 0.999 0.999 0.999 0.997 0.996
best 1.0 1.0 1.0 1.0 0.999 0.999

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.935 0.866 0.941 0.659
batch 2 0.818 0.662 0.849 0.66
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHeat shock factors {3.4} (TFClass)
TF familyHSF {3.4.1} (TFClass)
TF subfamily {3.4.1.0} (TFClass)
TFClass IDTFClass: 3.4.1.0.4
HGNCHGNC:5227
MGIMGI:1347058
EntrezGene (human)GeneID:3299
(SSTAR profile)
EntrezGene (mouse)GeneID:26386
(SSTAR profile)
UniProt ID (human)HSF4_HUMAN
UniProt ID (mouse)HSF4_MOUSE
UniProt AC (human)Q9ULV5
(TFClass)
UniProt AC (mouse)Q9R0L1
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01429.25558.25618.25711.25
02416.751202.75473.75223.75
03179.0394.0416.01328.0
041105.0463.0716.033.0
0517.024.02254.022.0
062098.0100.032.087.0
072123.032.066.096.0
08144.01056.0334.0783.0
09768.0322.01118.0109.0
1081.048.026.02162.0
1169.05.084.02159.0
124.02313.00.00.0
133.0323.0141.01850.0
141825.0167.0324.01.0
153.09.02305.00.0
161983.0136.071.0127.0
171842.0115.0124.0236.0
18292.25809.25546.25669.25
19597.5521.5812.5385.5
PFM
ACGT
010.1850.2410.2670.307
020.180.5190.2040.097
030.0770.170.180.573
040.4770.20.3090.014
050.0070.010.9730.009
060.9050.0430.0140.038
070.9160.0140.0280.041
080.0620.4560.1440.338
090.3310.1390.4830.047
100.0350.0210.0110.933
110.030.0020.0360.932
120.0020.9980.00.0
130.0010.1390.0610.798
140.7880.0720.140.0
150.0010.0040.9950.0
160.8560.0590.0310.055
170.7950.050.0540.102
180.1260.3490.2360.289
190.2580.2250.3510.166
PWM
ACGT
01-0.299-0.0370.0650.205
02-0.3280.729-0.2-0.946
03-1.167-0.384-0.330.828
040.644-0.2230.211-2.812
05-3.424-3.1091.356-3.19
061.285-1.741-2.841-1.877
071.296-2.841-2.146-1.781
08-1.3820.599-0.5480.301
090.281-0.5850.656-1.656
10-1.947-2.454-3.0351.315
11-2.103-4.428-1.9111.313
12-4.5841.382-5.704-5.704
13-4.768-0.581-1.4031.159
141.145-1.236-0.578-5.288
15-4.768-3.9731.379-5.704
161.228-1.438-2.075-1.506
171.155-1.603-1.529-0.893
18-0.6810.333-0.0580.144
190.031-0.1050.337-0.406
Standard thresholds
P-value Threshold
0.001 1.32996
0.0005 2.70336
0.0001 5.56886