MotifHNF6.H12INVIVO.2.S.B
Gene (human)ONECUT1
(GeneCards)
Gene synonyms (human)HNF6, HNF6A
Gene (mouse)Onecut1
Gene synonyms (mouse)Hnf6, Hnf6a
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
B
Motif length20
ConsensusnhhWATCGATYRWTdvnnnn
GC content37.48%
Information content (bits; total / per base)17.135 / 0.857
Data sourcesHT-SELEX
Aligned words251

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 12 (54) 0.873 0.909 0.835 0.886 0.809 0.847 2.696 3.048 275.696 396.367

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 10 experiments median 0.986 0.974 0.979 0.965 0.971 0.954
best 0.998 0.996 0.997 0.995 0.996 0.994
Methyl HT-SELEX, 3 experiments median 0.976 0.956 0.976 0.955 0.965 0.943
best 0.979 0.963 0.982 0.965 0.982 0.965
Non-Methyl HT-SELEX, 7 experiments median 0.992 0.985 0.991 0.984 0.976 0.967
best 0.998 0.996 0.997 0.995 0.996 0.994
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-CUT {3.1.9} (TFClass)
TF subfamilyONECUT {3.1.9.1} (TFClass)
TFClass IDTFClass: 3.1.9.1.1
HGNCHGNC:8138
MGIMGI:1196423
EntrezGene (human)GeneID:3175
(SSTAR profile)
EntrezGene (mouse)GeneID:15379
(SSTAR profile)
UniProt ID (human)HNF6_HUMAN
UniProt ID (mouse)HNF6_MOUSE
UniProt AC (human)Q9UBC0
(TFClass)
UniProt AC (mouse)O08755
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 12 mouse
HT-SELEX 7
Methyl-HT-SELEX 3
PCM
ACGT
0177.2587.2548.2538.25
02134.2549.2527.2540.25
03100.048.026.077.0
0492.00.010.0149.0
05251.00.00.00.0
060.00.00.0251.0
070.0250.00.01.0
080.00.0251.00.0
09251.00.00.00.0
100.00.00.0251.0
1126.0141.00.084.0
1256.08.0175.012.0
13182.017.023.029.0
145.021.010.0215.0
1584.032.048.087.0
1681.058.082.030.0
1786.050.041.074.0
1838.055.055.0103.0
1951.2547.2595.2557.25
2058.551.574.566.5
PFM
ACGT
010.3080.3480.1920.152
020.5350.1960.1090.16
030.3980.1910.1040.307
040.3670.00.040.594
051.00.00.00.0
060.00.00.01.0
070.00.9960.00.004
080.00.01.00.0
091.00.00.00.0
100.00.00.01.0
110.1040.5620.00.335
120.2230.0320.6970.048
130.7250.0680.0920.116
140.020.0840.040.857
150.3350.1270.1910.347
160.3230.2310.3270.12
170.3430.1990.1630.295
180.1510.2190.2190.41
190.2040.1880.3790.228
200.2330.2050.2970.265
PWM
ACGT
010.2040.324-0.256-0.481
020.749-0.236-0.806-0.432
030.458-0.261-0.8510.201
040.376-3.838-1.7290.852
051.37-3.838-3.838-3.838
06-3.838-3.838-3.8381.37
07-3.8381.366-3.838-3.293
08-3.838-3.8381.37-3.838
091.37-3.838-3.838-3.838
10-3.838-3.838-3.8381.37
11-0.8510.798-3.8380.286
12-0.111-1.9221.012-1.567
131.051-1.25-0.967-0.747
14-2.308-1.053-1.7291.216
150.286-0.653-0.2610.321
160.25-0.0770.262-0.715
170.309-0.222-0.4140.162
18-0.488-0.129-0.1290.487
19-0.198-0.2770.41-0.09
20-0.069-0.1930.1680.057
Standard thresholds
P-value Threshold
0.001 1.77221
0.0005 3.14346
0.0001 5.98796