MotifHNF6.H12INVITRO.3.M.B
Gene (human)ONECUT1
(GeneCards)
Gene synonyms (human)HNF6, HNF6A
Gene (mouse)Onecut1
Gene synonyms (mouse)Hnf6, Hnf6a
LOGO
LOGO (reverse complement)
Motif subtype3
Quality
B
Motif length15
ConsensusnvKTATTGATTRRTb
GC content28.33%
Information content (bits; total / per base)19.196 / 1.28
Data sourcesMethyl-HT-SELEX
Aligned words1173

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 12 (54) 0.747 0.832 0.723 0.804 0.848 0.898 3.412 3.934 320.93 464.409

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 10 experiments median 0.988 0.981 0.973 0.96 0.946 0.927
best 0.999 0.997 0.998 0.997 0.998 0.996
Methyl HT-SELEX, 3 experiments median 0.995 0.991 0.993 0.988 0.976 0.968
best 0.999 0.997 0.998 0.997 0.998 0.996
Non-Methyl HT-SELEX, 7 experiments median 0.983 0.971 0.96 0.939 0.927 0.903
best 0.995 0.991 0.986 0.98 0.972 0.959
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-CUT {3.1.9} (TFClass)
TF subfamilyONECUT {3.1.9.1} (TFClass)
TFClass IDTFClass: 3.1.9.1.1
HGNCHGNC:8138
MGIMGI:1196423
EntrezGene (human)GeneID:3175
(SSTAR profile)
EntrezGene (mouse)GeneID:15379
(SSTAR profile)
UniProt ID (human)HNF6_HUMAN
UniProt ID (mouse)HNF6_MOUSE
UniProt AC (human)Q9UBC0
(TFClass)
UniProt AC (mouse)O08755
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 12 mouse
HT-SELEX 7
Methyl-HT-SELEX 3
PCM
ACGT
01300.5312.5331.5228.5
02342.0236.0444.0151.0
0358.039.0518.0558.0
040.00.00.01173.0
051173.00.00.00.0
060.00.00.01173.0
070.00.00.01173.0
080.00.01173.00.0
091173.00.00.00.0
100.00.00.01173.0
110.082.00.01091.0
12189.03.0888.093.0
13824.025.0206.0118.0
1427.0165.051.0930.0
15160.5278.5232.5501.5
PFM
ACGT
010.2560.2660.2830.195
020.2920.2010.3790.129
030.0490.0330.4420.476
040.00.00.01.0
051.00.00.00.0
060.00.00.01.0
070.00.00.01.0
080.00.01.00.0
091.00.00.00.0
100.00.00.01.0
110.00.070.00.93
120.1610.0030.7570.079
130.7020.0210.1760.101
140.0230.1410.0430.793
150.1370.2370.1980.428
PWM
ACGT
010.0240.0630.122-0.248
020.153-0.2160.413-0.658
03-1.597-1.9790.5660.64
04-5.118-5.118-5.1181.382
051.382-5.118-5.118-5.118
06-5.118-5.118-5.1181.382
07-5.118-5.118-5.1181.382
08-5.118-5.1181.382-5.118
091.382-5.118-5.118-5.118
10-5.118-5.118-5.1181.382
11-5.118-1.259-5.1181.309
12-0.436-4.1251.104-1.136
131.029-2.4-0.351-0.901
14-2.328-0.57-1.7211.15
15-0.598-0.051-0.2310.534
Standard thresholds
P-value Threshold
0.001 -2.01994
0.0005 -0.24022
0.0001 3.73527