Motif | HNF1B.H12CORE.0.PS.A |
Gene (human) | HNF1B (GeneCards) |
Gene synonyms (human) | TCF2 |
Gene (mouse) | Hnf1b |
Gene synonyms (mouse) | Hnf-1b, Tcf2 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | A |
Motif | HNF1B.H12CORE.0.PS.A |
Gene (human) | HNF1B (GeneCards) |
Gene synonyms (human) | TCF2 |
Gene (mouse) | Hnf1b |
Gene synonyms (mouse) | Hnf-1b, Tcf2 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | A |
Motif length | 15 |
Consensus | dRTWAATGATTRAYh |
GC content | 26.05% |
Information content (bits; total / per base) | 15.226 / 1.015 |
Data sources | ChIP-Seq + HT-SELEX |
Aligned words | 1000 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 4 (24) | 0.953 | 0.979 | 0.928 | 0.958 | 0.97 | 0.987 | 5.825 | 6.194 | 265.041 | 479.237 |
Mouse | 4 (27) | 0.977 | 0.984 | 0.957 | 0.97 | 0.982 | 0.988 | 5.803 | 6.473 | 574.678 | 772.018 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Non-Methyl HT-SELEX, 2 experiments | median | 1.0 | 1.0 | 0.998 | 0.997 | 0.848 | 0.882 |
best | 1 | 1 | 1.0 | 1.0 | 0.92 | 0.938 |
rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
---|---|---|---|---|
batch 1 | 0.942 | 0.434 | 0.937 | 0.564 |
batch 2 | 0.913 | 0.62 | 0.913 | 0.63 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | POU {3.1.10} (TFClass) |
TF subfamily | HNF1-like {3.1.10.7} (TFClass) |
TFClass ID | TFClass: 3.1.10.7.2 |
HGNC | HGNC:11630 |
MGI | MGI:98505 |
EntrezGene (human) | GeneID:6928 (SSTAR profile) |
EntrezGene (mouse) | GeneID:21410 (SSTAR profile) |
UniProt ID (human) | HNF1B_HUMAN |
UniProt ID (mouse) | HNF1B_MOUSE |
UniProt AC (human) | P35680 (TFClass) |
UniProt AC (mouse) | P27889 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 4 human, 4 mouse |
HT-SELEX | 2 |
Methyl-HT-SELEX | 0 |
PCM | HNF1B.H12CORE.0.PS.A.pcm |
PWM | HNF1B.H12CORE.0.PS.A.pwm |
PFM | HNF1B.H12CORE.0.PS.A.pfm |
Alignment | HNF1B.H12CORE.0.PS.A.words.tsv |
Threshold to P-value map | HNF1B.H12CORE.0.PS.A.thr |
Motif in other formats | |
JASPAR format | HNF1B.H12CORE.0.PS.A_jaspar_format.txt |
MEME format | HNF1B.H12CORE.0.PS.A_meme_format.meme |
Transfac format | HNF1B.H12CORE.0.PS.A_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 326.0 | 78.0 | 347.0 | 249.0 |
02 | 163.0 | 29.0 | 733.0 | 75.0 |
03 | 25.0 | 83.0 | 69.0 | 823.0 |
04 | 133.0 | 72.0 | 35.0 | 760.0 |
05 | 969.0 | 2.0 | 23.0 | 6.0 |
06 | 941.0 | 44.0 | 3.0 | 12.0 |
07 | 41.0 | 12.0 | 4.0 | 943.0 |
08 | 397.0 | 0.0 | 603.0 | 0.0 |
09 | 778.0 | 14.0 | 49.0 | 159.0 |
10 | 63.0 | 24.0 | 113.0 | 800.0 |
11 | 13.0 | 40.0 | 1.0 | 946.0 |
12 | 699.0 | 59.0 | 137.0 | 105.0 |
13 | 825.0 | 83.0 | 61.0 | 31.0 |
14 | 71.0 | 704.0 | 39.0 | 186.0 |
15 | 235.0 | 361.0 | 86.0 | 318.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.326 | 0.078 | 0.347 | 0.249 |
02 | 0.163 | 0.029 | 0.733 | 0.075 |
03 | 0.025 | 0.083 | 0.069 | 0.823 |
04 | 0.133 | 0.072 | 0.035 | 0.76 |
05 | 0.969 | 0.002 | 0.023 | 0.006 |
06 | 0.941 | 0.044 | 0.003 | 0.012 |
07 | 0.041 | 0.012 | 0.004 | 0.943 |
08 | 0.397 | 0.0 | 0.603 | 0.0 |
09 | 0.778 | 0.014 | 0.049 | 0.159 |
10 | 0.063 | 0.024 | 0.113 | 0.8 |
11 | 0.013 | 0.04 | 0.001 | 0.946 |
12 | 0.699 | 0.059 | 0.137 | 0.105 |
13 | 0.825 | 0.083 | 0.061 | 0.031 |
14 | 0.071 | 0.704 | 0.039 | 0.186 |
15 | 0.235 | 0.361 | 0.086 | 0.318 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.264 | -1.15 | 0.326 | -0.004 |
02 | -0.424 | -2.103 | 1.071 | -1.188 |
03 | -2.243 | -1.089 | -1.27 | 1.187 |
04 | -0.625 | -1.228 | -1.925 | 1.107 |
05 | 1.35 | -4.213 | -2.32 | -3.484 |
06 | 1.32 | -1.706 | -3.975 | -2.909 |
07 | -1.774 | -2.909 | -3.783 | 1.323 |
08 | 0.46 | -4.982 | 0.876 | -4.982 |
09 | 1.131 | -2.773 | -1.602 | -0.449 |
10 | -1.358 | -2.281 | -0.786 | 1.158 |
11 | -2.839 | -1.797 | -4.525 | 1.326 |
12 | 1.024 | -1.422 | -0.596 | -0.858 |
13 | 1.189 | -1.089 | -1.39 | -2.04 |
14 | -1.242 | 1.031 | -1.821 | -0.293 |
15 | -0.061 | 0.365 | -1.054 | 0.239 |
P-value | Threshold |
---|---|
0.001 | 3.04256 |
0.0005 | 4.17751 |
0.0001 | 6.54806 |