MotifHMX3.H12INVIVO.0.S.D
Gene (human)HMX3
(GeneCards)
Gene synonyms (human)NKX-5.1, NKX5-1
Gene (mouse)Hmx3
Gene synonyms (mouse)Nkx-5.1, Nkx5-1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length13
ConsensusnvvTTAATTGvbn
GC content35.15%
Information content (bits; total / per base)13.513 / 1.039
Data sourcesHT-SELEX
Aligned words674

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 2 experiments median 0.944 0.916 0.877 0.849 0.745 0.744
best 0.969 0.951 0.926 0.902 0.785 0.787

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.996 0.771 0.961 0.533
batch 2 0.905 0.147 0.85 0.385
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyNK5-HMX {3.1.2.18} (TFClass)
TFClass IDTFClass: 3.1.2.18.3
HGNCHGNC:5019
MGIMGI:107160
EntrezGene (human)GeneID:340784
(SSTAR profile)
EntrezGene (mouse)GeneID:15373
(SSTAR profile)
UniProt ID (human)HMX3_HUMAN
UniProt ID (mouse)HMX3_MOUSE
UniProt AC (human)A6NHT5
(TFClass)
UniProt AC (mouse)P42581
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 2
Methyl-HT-SELEX 0
PCM
ACGT
01114.0212.0151.0197.0
02217.75162.75210.7582.75
03204.0247.0155.068.0
042.018.02.0652.0
050.02.00.0672.0
06674.00.00.00.0
07674.00.00.00.0
080.00.0161.0513.0
090.010.00.0664.0
100.00.0674.00.0
11150.0281.0155.088.0
1255.75234.7584.75298.75
13166.0210.0109.0189.0
PFM
ACGT
010.1690.3150.2240.292
020.3230.2410.3130.123
030.3030.3660.230.101
040.0030.0270.0030.967
050.00.0030.00.997
061.00.00.00.0
071.00.00.00.0
080.00.00.2390.761
090.00.0150.00.985
100.00.01.00.0
110.2230.4170.230.131
120.0830.3480.1260.443
130.2460.3120.1620.28
PWM
ACGT
01-0.3860.228-0.1090.155
020.254-0.0340.222-0.701
030.190.379-0.083-0.893
04-3.848-2.16-3.8481.346
05-4.649-3.848-4.6491.376
061.379-4.649-4.649-4.649
071.379-4.649-4.649-4.649
08-4.649-4.649-0.0451.107
09-4.649-2.683-4.6491.364
10-4.649-4.6491.379-4.649
11-0.1150.508-0.083-0.641
12-1.0870.329-0.6780.568
13-0.0150.218-0.430.114
Standard thresholds
P-value Threshold
0.001 3.02986
0.0005 3.99016
0.0001 7.178125