Motif | HMX3.H12CORE.0.S.B |
Gene (human) | HMX3 (GeneCards) |
Gene synonyms (human) | NKX-5.1, NKX5-1 |
Gene (mouse) | Hmx3 |
Gene synonyms (mouse) | Nkx-5.1, Nkx5-1 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif | HMX3.H12CORE.0.S.B |
Gene (human) | HMX3 (GeneCards) |
Gene synonyms (human) | NKX-5.1, NKX5-1 |
Gene (mouse) | Hmx3 |
Gene synonyms (mouse) | Nkx-5.1, Nkx5-1 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif length | 13 |
Consensus | nvvTTAATTGvbn |
GC content | 35.15% |
Information content (bits; total / per base) | 13.513 / 1.039 |
Data sources | HT-SELEX |
Aligned words | 674 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Non-Methyl HT-SELEX, 2 experiments | median | 0.944 | 0.916 | 0.877 | 0.849 | 0.745 | 0.744 |
best | 0.969 | 0.951 | 0.926 | 0.902 | 0.785 | 0.787 |
rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
---|---|---|---|---|
batch 1 | 0.996 | 0.771 | 0.961 | 0.533 |
batch 2 | 0.905 | 0.147 | 0.85 | 0.385 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | NK-related {3.1.2} (TFClass) |
TF subfamily | NK5-HMX {3.1.2.18} (TFClass) |
TFClass ID | TFClass: 3.1.2.18.3 |
HGNC | HGNC:5019 |
MGI | MGI:107160 |
EntrezGene (human) | GeneID:340784 (SSTAR profile) |
EntrezGene (mouse) | GeneID:15373 (SSTAR profile) |
UniProt ID (human) | HMX3_HUMAN |
UniProt ID (mouse) | HMX3_MOUSE |
UniProt AC (human) | A6NHT5 (TFClass) |
UniProt AC (mouse) | P42581 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 0 mouse |
HT-SELEX | 2 |
Methyl-HT-SELEX | 0 |
PCM | HMX3.H12CORE.0.S.B.pcm |
PWM | HMX3.H12CORE.0.S.B.pwm |
PFM | HMX3.H12CORE.0.S.B.pfm |
Alignment | HMX3.H12CORE.0.S.B.words.tsv |
Threshold to P-value map | HMX3.H12CORE.0.S.B.thr |
Motif in other formats | |
JASPAR format | HMX3.H12CORE.0.S.B_jaspar_format.txt |
MEME format | HMX3.H12CORE.0.S.B_meme_format.meme |
Transfac format | HMX3.H12CORE.0.S.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 114.0 | 212.0 | 151.0 | 197.0 |
02 | 217.75 | 162.75 | 210.75 | 82.75 |
03 | 204.0 | 247.0 | 155.0 | 68.0 |
04 | 2.0 | 18.0 | 2.0 | 652.0 |
05 | 0.0 | 2.0 | 0.0 | 672.0 |
06 | 674.0 | 0.0 | 0.0 | 0.0 |
07 | 674.0 | 0.0 | 0.0 | 0.0 |
08 | 0.0 | 0.0 | 161.0 | 513.0 |
09 | 0.0 | 10.0 | 0.0 | 664.0 |
10 | 0.0 | 0.0 | 674.0 | 0.0 |
11 | 150.0 | 281.0 | 155.0 | 88.0 |
12 | 55.75 | 234.75 | 84.75 | 298.75 |
13 | 166.0 | 210.0 | 109.0 | 189.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.169 | 0.315 | 0.224 | 0.292 |
02 | 0.323 | 0.241 | 0.313 | 0.123 |
03 | 0.303 | 0.366 | 0.23 | 0.101 |
04 | 0.003 | 0.027 | 0.003 | 0.967 |
05 | 0.0 | 0.003 | 0.0 | 0.997 |
06 | 1.0 | 0.0 | 0.0 | 0.0 |
07 | 1.0 | 0.0 | 0.0 | 0.0 |
08 | 0.0 | 0.0 | 0.239 | 0.761 |
09 | 0.0 | 0.015 | 0.0 | 0.985 |
10 | 0.0 | 0.0 | 1.0 | 0.0 |
11 | 0.223 | 0.417 | 0.23 | 0.131 |
12 | 0.083 | 0.348 | 0.126 | 0.443 |
13 | 0.246 | 0.312 | 0.162 | 0.28 |
A | C | G | T | |
---|---|---|---|---|
01 | -0.386 | 0.228 | -0.109 | 0.155 |
02 | 0.254 | -0.034 | 0.222 | -0.701 |
03 | 0.19 | 0.379 | -0.083 | -0.893 |
04 | -3.848 | -2.16 | -3.848 | 1.346 |
05 | -4.649 | -3.848 | -4.649 | 1.376 |
06 | 1.379 | -4.649 | -4.649 | -4.649 |
07 | 1.379 | -4.649 | -4.649 | -4.649 |
08 | -4.649 | -4.649 | -0.045 | 1.107 |
09 | -4.649 | -2.683 | -4.649 | 1.364 |
10 | -4.649 | -4.649 | 1.379 | -4.649 |
11 | -0.115 | 0.508 | -0.083 | -0.641 |
12 | -1.087 | 0.329 | -0.678 | 0.568 |
13 | -0.015 | 0.218 | -0.43 | 0.114 |
P-value | Threshold |
---|---|
0.001 | 3.02986 |
0.0005 | 3.99016 |
0.0001 | 7.178125 |