| Motif | HMX2.H12INVITRO.0.SM.B |
| Gene (human) | HMX2 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Hmx2 |
| Gene synonyms (mouse) | Nkx-5.2, Nkx5-2 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | HMX2.H12INVITRO.0.SM.B |
| Gene (human) | HMX2 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Hmx2 |
| Gene synonyms (mouse) | Nkx-5.2, Nkx5-2 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 11 |
| Consensus | nWTAAKTGvbn |
| GC content | 36.34% |
| Information content (bits; total / per base) | 9.949 / 0.904 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 9309 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 6 experiments | median | 0.934 | 0.898 | 0.885 | 0.844 | 0.805 | 0.77 |
| best | 0.985 | 0.976 | 0.966 | 0.951 | 0.919 | 0.899 | |
| Methyl HT-SELEX, 2 experiments | median | 0.955 | 0.93 | 0.923 | 0.892 | 0.858 | 0.829 |
| best | 0.985 | 0.976 | 0.96 | 0.945 | 0.893 | 0.875 | |
| Non-Methyl HT-SELEX, 4 experiments | median | 0.916 | 0.873 | 0.865 | 0.819 | 0.782 | 0.749 |
| best | 0.984 | 0.974 | 0.966 | 0.951 | 0.919 | 0.899 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | NK-related {3.1.2} (TFClass) |
| TF subfamily | NK5-HMX {3.1.2.18} (TFClass) |
| TFClass ID | TFClass: 3.1.2.18.2 |
| HGNC | HGNC:5018 |
| MGI | MGI:107159 |
| EntrezGene (human) | GeneID:3167 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:15372 (SSTAR profile) |
| UniProt ID (human) | HMX2_HUMAN |
| UniProt ID (mouse) | HMX2_MOUSE |
| UniProt AC (human) | A2RU54 (TFClass) |
| UniProt AC (mouse) | P43687 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 4 |
| Methyl-HT-SELEX | 2 |
| PCM | HMX2.H12INVITRO.0.SM.B.pcm |
| PWM | HMX2.H12INVITRO.0.SM.B.pwm |
| PFM | HMX2.H12INVITRO.0.SM.B.pfm |
| Alignment | HMX2.H12INVITRO.0.SM.B.words.tsv |
| Threshold to P-value map | HMX2.H12INVITRO.0.SM.B.thr |
| Motif in other formats | |
| JASPAR format | HMX2.H12INVITRO.0.SM.B_jaspar_format.txt |
| MEME format | HMX2.H12INVITRO.0.SM.B_meme_format.meme |
| Transfac format | HMX2.H12INVITRO.0.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 2413.25 | 1654.25 | 2905.25 | 2336.25 |
| 02 | 951.25 | 564.25 | 579.25 | 7214.25 |
| 03 | 432.0 | 800.0 | 102.0 | 7975.0 |
| 04 | 8820.0 | 0.0 | 487.0 | 2.0 |
| 05 | 9309.0 | 0.0 | 0.0 | 0.0 |
| 06 | 383.0 | 51.0 | 4707.0 | 4168.0 |
| 07 | 0.0 | 1447.0 | 2.0 | 7860.0 |
| 08 | 315.0 | 20.0 | 8919.0 | 55.0 |
| 09 | 1677.0 | 2610.0 | 3551.0 | 1471.0 |
| 10 | 1194.5 | 2679.5 | 1562.5 | 3872.5 |
| 11 | 1769.0 | 2699.0 | 1871.0 | 2970.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.259 | 0.178 | 0.312 | 0.251 |
| 02 | 0.102 | 0.061 | 0.062 | 0.775 |
| 03 | 0.046 | 0.086 | 0.011 | 0.857 |
| 04 | 0.947 | 0.0 | 0.052 | 0.0 |
| 05 | 1.0 | 0.0 | 0.0 | 0.0 |
| 06 | 0.041 | 0.005 | 0.506 | 0.448 |
| 07 | 0.0 | 0.155 | 0.0 | 0.844 |
| 08 | 0.034 | 0.002 | 0.958 | 0.006 |
| 09 | 0.18 | 0.28 | 0.381 | 0.158 |
| 10 | 0.128 | 0.288 | 0.168 | 0.416 |
| 11 | 0.19 | 0.29 | 0.201 | 0.319 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.036 | -0.341 | 0.222 | 0.004 |
| 02 | -0.893 | -1.414 | -1.388 | 1.131 |
| 03 | -1.68 | -1.066 | -3.106 | 1.231 |
| 04 | 1.332 | -6.927 | -1.56 | -6.298 |
| 05 | 1.386 | -6.927 | -6.927 | -6.927 |
| 06 | -1.799 | -3.778 | 0.704 | 0.582 |
| 07 | -6.927 | -0.475 | -6.298 | 1.216 |
| 08 | -1.994 | -4.65 | 1.343 | -3.705 |
| 09 | -0.327 | 0.115 | 0.422 | -0.458 |
| 10 | -0.666 | 0.141 | -0.398 | 0.509 |
| 11 | -0.274 | 0.148 | -0.218 | 0.244 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.91907 |
| 0.0005 | 5.830205 |
| 0.0001 | 7.531835 |