MotifHMX2.H12CORE.0.SM.B
Gene (human)HMX2
(GeneCards)
Gene synonyms (human)
Gene (mouse)Hmx2
Gene synonyms (mouse)Nkx-5.2, Nkx5-2
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length11
ConsensusnWTAAKTGvbn
GC content36.34%
Information content (bits; total / per base)9.949 / 0.904
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9309

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.934 0.898 0.885 0.844 0.805 0.77
best 0.985 0.976 0.966 0.951 0.919 0.899
Methyl HT-SELEX, 2 experiments median 0.955 0.93 0.923 0.892 0.858 0.829
best 0.985 0.976 0.96 0.945 0.893 0.875
Non-Methyl HT-SELEX, 4 experiments median 0.916 0.873 0.865 0.819 0.782 0.749
best 0.984 0.974 0.966 0.951 0.919 0.899
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyNK5-HMX {3.1.2.18} (TFClass)
TFClass IDTFClass: 3.1.2.18.2
HGNCHGNC:5018
MGIMGI:107159
EntrezGene (human)GeneID:3167
(SSTAR profile)
EntrezGene (mouse)GeneID:15372
(SSTAR profile)
UniProt ID (human)HMX2_HUMAN
UniProt ID (mouse)HMX2_MOUSE
UniProt AC (human)A2RU54
(TFClass)
UniProt AC (mouse)P43687
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 4
Methyl-HT-SELEX 2
PCM
ACGT
012413.251654.252905.252336.25
02951.25564.25579.257214.25
03432.0800.0102.07975.0
048820.00.0487.02.0
059309.00.00.00.0
06383.051.04707.04168.0
070.01447.02.07860.0
08315.020.08919.055.0
091677.02610.03551.01471.0
101194.52679.51562.53872.5
111769.02699.01871.02970.0
PFM
ACGT
010.2590.1780.3120.251
020.1020.0610.0620.775
030.0460.0860.0110.857
040.9470.00.0520.0
051.00.00.00.0
060.0410.0050.5060.448
070.00.1550.00.844
080.0340.0020.9580.006
090.180.280.3810.158
100.1280.2880.1680.416
110.190.290.2010.319
PWM
ACGT
010.036-0.3410.2220.004
02-0.893-1.414-1.3881.131
03-1.68-1.066-3.1061.231
041.332-6.927-1.56-6.298
051.386-6.927-6.927-6.927
06-1.799-3.7780.7040.582
07-6.927-0.475-6.2981.216
08-1.994-4.651.343-3.705
09-0.3270.1150.422-0.458
10-0.6660.141-0.3980.509
11-0.2740.148-0.2180.244
Standard thresholds
P-value Threshold
0.001 4.91907
0.0005 5.830205
0.0001 7.531835