MotifHMX1.H12CORE.0.SM.B
Gene (human)HMX1
(GeneCards)
Gene synonyms (human)H6
Gene (mouse)Hmx1
Gene synonyms (mouse)H6
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length11
ConsensusnTTAATTGnhh
GC content29.59%
Information content (bits; total / per base)12.136 / 1.103
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words2169

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.841 0.796 0.778 0.744 0.721 0.698
best 0.941 0.898 0.916 0.872 0.862 0.82
Methyl HT-SELEX, 1 experiments median 0.941 0.898 0.916 0.872 0.86 0.82
best 0.941 0.898 0.916 0.872 0.86 0.82
Non-Methyl HT-SELEX, 3 experiments median 0.756 0.712 0.652 0.634 0.582 0.584
best 0.926 0.88 0.904 0.854 0.862 0.813

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.782 0.567 0.795 0.587
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyNK5-HMX {3.1.2.18} (TFClass)
TFClass IDTFClass: 3.1.2.18.1
HGNCHGNC:5017
MGIMGI:107178
EntrezGene (human)GeneID:3166
(SSTAR profile)
EntrezGene (mouse)GeneID:15371
(SSTAR profile)
UniProt ID (human)HMX1_HUMAN
UniProt ID (mouse)HMX1_MOUSE
UniProt AC (human)Q9NP08
(TFClass)
UniProt AC (mouse)O70218
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01779.25453.25478.25458.25
0298.0111.071.01889.0
0316.0117.01.02035.0
042168.00.01.00.0
052169.00.00.00.0
060.00.0691.01478.0
070.073.00.02096.0
0812.00.02157.00.0
09524.0778.0417.0450.0
10278.5584.5232.51073.5
11482.0599.0296.0792.0
PFM
ACGT
010.3590.2090.220.211
020.0450.0510.0330.871
030.0070.0540.00.938
041.00.00.00.0
051.00.00.00.0
060.00.00.3190.681
070.00.0340.00.966
080.0060.00.9940.0
090.2420.3590.1920.207
100.1280.2690.1070.495
110.2220.2760.1360.365
PWM
ACGT
010.362-0.179-0.125-0.168
02-1.695-1.573-2.011.246
03-3.413-1.521-5.2281.32
041.383-5.647-5.228-5.647
051.384-5.647-5.647-5.647
06-5.647-5.6470.2421.0
07-5.647-1.983-5.6471.349
08-3.666-5.6471.378-5.647
09-0.0340.36-0.262-0.186
10-0.6630.075-0.8420.681
11-0.1170.099-0.6020.378
Standard thresholds
P-value Threshold
0.001 3.347085
0.0005 5.072985
0.0001 7.581865