| Motif | HMX1.H12CORE.0.SM.B |
| Gene (human) | HMX1 (GeneCards) |
| Gene synonyms (human) | H6 |
| Gene (mouse) | Hmx1 |
| Gene synonyms (mouse) | H6 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | HMX1.H12CORE.0.SM.B |
| Gene (human) | HMX1 (GeneCards) |
| Gene synonyms (human) | H6 |
| Gene (mouse) | Hmx1 |
| Gene synonyms (mouse) | H6 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 11 |
| Consensus | nTTAATTGnhh |
| GC content | 29.59% |
| Information content (bits; total / per base) | 12.136 / 1.103 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 2169 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.841 | 0.796 | 0.778 | 0.744 | 0.721 | 0.698 |
| best | 0.941 | 0.898 | 0.916 | 0.872 | 0.862 | 0.82 | |
| Methyl HT-SELEX, 1 experiments | median | 0.941 | 0.898 | 0.916 | 0.872 | 0.86 | 0.82 |
| best | 0.941 | 0.898 | 0.916 | 0.872 | 0.86 | 0.82 | |
| Non-Methyl HT-SELEX, 3 experiments | median | 0.756 | 0.712 | 0.652 | 0.634 | 0.582 | 0.584 |
| best | 0.926 | 0.88 | 0.904 | 0.854 | 0.862 | 0.813 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 2 | 0.782 | 0.567 | 0.795 | 0.587 |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | NK-related {3.1.2} (TFClass) |
| TF subfamily | NK5-HMX {3.1.2.18} (TFClass) |
| TFClass ID | TFClass: 3.1.2.18.1 |
| HGNC | HGNC:5017 |
| MGI | MGI:107178 |
| EntrezGene (human) | GeneID:3166 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:15371 (SSTAR profile) |
| UniProt ID (human) | HMX1_HUMAN |
| UniProt ID (mouse) | HMX1_MOUSE |
| UniProt AC (human) | Q9NP08 (TFClass) |
| UniProt AC (mouse) | O70218 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 3 |
| Methyl-HT-SELEX | 1 |
| PCM | HMX1.H12CORE.0.SM.B.pcm |
| PWM | HMX1.H12CORE.0.SM.B.pwm |
| PFM | HMX1.H12CORE.0.SM.B.pfm |
| Alignment | HMX1.H12CORE.0.SM.B.words.tsv |
| Threshold to P-value map | HMX1.H12CORE.0.SM.B.thr |
| Motif in other formats | |
| JASPAR format | HMX1.H12CORE.0.SM.B_jaspar_format.txt |
| MEME format | HMX1.H12CORE.0.SM.B_meme_format.meme |
| Transfac format | HMX1.H12CORE.0.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 779.25 | 453.25 | 478.25 | 458.25 |
| 02 | 98.0 | 111.0 | 71.0 | 1889.0 |
| 03 | 16.0 | 117.0 | 1.0 | 2035.0 |
| 04 | 2168.0 | 0.0 | 1.0 | 0.0 |
| 05 | 2169.0 | 0.0 | 0.0 | 0.0 |
| 06 | 0.0 | 0.0 | 691.0 | 1478.0 |
| 07 | 0.0 | 73.0 | 0.0 | 2096.0 |
| 08 | 12.0 | 0.0 | 2157.0 | 0.0 |
| 09 | 524.0 | 778.0 | 417.0 | 450.0 |
| 10 | 278.5 | 584.5 | 232.5 | 1073.5 |
| 11 | 482.0 | 599.0 | 296.0 | 792.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.359 | 0.209 | 0.22 | 0.211 |
| 02 | 0.045 | 0.051 | 0.033 | 0.871 |
| 03 | 0.007 | 0.054 | 0.0 | 0.938 |
| 04 | 1.0 | 0.0 | 0.0 | 0.0 |
| 05 | 1.0 | 0.0 | 0.0 | 0.0 |
| 06 | 0.0 | 0.0 | 0.319 | 0.681 |
| 07 | 0.0 | 0.034 | 0.0 | 0.966 |
| 08 | 0.006 | 0.0 | 0.994 | 0.0 |
| 09 | 0.242 | 0.359 | 0.192 | 0.207 |
| 10 | 0.128 | 0.269 | 0.107 | 0.495 |
| 11 | 0.222 | 0.276 | 0.136 | 0.365 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.362 | -0.179 | -0.125 | -0.168 |
| 02 | -1.695 | -1.573 | -2.01 | 1.246 |
| 03 | -3.413 | -1.521 | -5.228 | 1.32 |
| 04 | 1.383 | -5.647 | -5.228 | -5.647 |
| 05 | 1.384 | -5.647 | -5.647 | -5.647 |
| 06 | -5.647 | -5.647 | 0.242 | 1.0 |
| 07 | -5.647 | -1.983 | -5.647 | 1.349 |
| 08 | -3.666 | -5.647 | 1.378 | -5.647 |
| 09 | -0.034 | 0.36 | -0.262 | -0.186 |
| 10 | -0.663 | 0.075 | -0.842 | 0.681 |
| 11 | -0.117 | 0.099 | -0.602 | 0.378 |
| P-value | Threshold |
|---|---|
| 0.001 | 3.347085 |
| 0.0005 | 5.072985 |
| 0.0001 | 7.581865 |