MotifHME2.H12INVIVO.0.SM.D
Gene (human)EN2
(GeneCards)
Gene synonyms (human)
Gene (mouse)En2
Gene synonyms (mouse)En-2
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length10
ConsensusnbRATTAvbn
GC content35.46%
Information content (bits; total / per base)8.292 / 0.829
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9153

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.828 0.79 0.716 0.692 0.632 0.627
best 0.991 0.986 0.98 0.971 0.952 0.936
Methyl HT-SELEX, 2 experiments median 0.91 0.884 0.852 0.833 0.792 0.781
best 0.991 0.986 0.98 0.971 0.95 0.935
Non-Methyl HT-SELEX, 6 experiments median 0.825 0.79 0.706 0.688 0.629 0.624
best 0.99 0.984 0.98 0.969 0.952 0.936
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyEN {3.1.2.7} (TFClass)
TFClass IDTFClass: 3.1.2.7.2
HGNCHGNC:3343
MGIMGI:95390
EntrezGene (human)GeneID:2020
(SSTAR profile)
EntrezGene (mouse)GeneID:13799
(SSTAR profile)
UniProt ID (human)HME2_HUMAN
UniProt ID (mouse)HME2_MOUSE
UniProt AC (human)P19622
(TFClass)
UniProt AC (mouse)P09066
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 6
Methyl-HT-SELEX 2
PCM
ACGT
012189.752668.752118.752175.75
02627.754276.75790.753457.75
036380.01258.01287.0228.0
048931.0142.080.00.0
050.09.01.09143.0
060.0689.00.08464.0
078162.0364.0578.049.0
081658.02550.04305.0640.0
09996.753018.753140.751996.75
102154.52241.52939.51817.5
PFM
ACGT
010.2390.2920.2310.238
020.0690.4670.0860.378
030.6970.1370.1410.025
040.9760.0160.0090.0
050.00.0010.00.999
060.00.0750.00.925
070.8920.040.0630.005
080.1810.2790.470.07
090.1090.330.3430.218
100.2350.2450.3210.199
PWM
ACGT
01-0.0440.154-0.077-0.05
02-1.2910.625-1.0610.412
031.025-0.597-0.575-2.297
041.361-2.765-3.326-6.912
05-6.912-5.313-6.5491.384
06-6.912-1.198-6.9121.307
071.271-1.833-1.373-3.799
08-0.3220.1080.632-1.272
09-0.830.2770.316-0.136
10-0.06-0.0210.25-0.23
Standard thresholds
P-value Threshold
0.001 5.322615
0.0005 5.978135
0.0001 7.332785