HLF.H12INVIVO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	HLF.H12INVIVO.0.P.B
Gene (human)	HLF (GeneCards)
Gene synonyms (human)
Gene (mouse)	Hlf
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	10
Consensus	RTTATGCAAY
GC content	34.2%
Information content (bits; total / per base)	13.869 / 1.387
Data sources	ChIP-Seq
Aligned words	986

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.985	0.986	0.97	0.971	0.981	0.982	5.22	5.324	1065.569	1091.046
Mouse	3 (16)	0.921	0.952	0.868	0.897	0.895	0.93	3.51	3.814	403.663	465.585

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.834	0.809	0.68	0.683	0.59	0.609
Overall, 6 experiments	best	0.989	0.979	0.982	0.971	0.955	0.939
Methyl HT-SELEX, 1 experiments	median	0.989	0.979	0.982	0.971	0.955	0.939
Methyl HT-SELEX, 1 experiments	best	0.989	0.979	0.982	0.971	0.955	0.939
Non-Methyl HT-SELEX, 5 experiments	median	0.764	0.753	0.632	0.64	0.569	0.583
Non-Methyl HT-SELEX, 5 experiments	best	0.985	0.973	0.977	0.962	0.945	0.926

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	9.986	5.021	0.273	0.18

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.872	0.27	0.855	0.507
batch 2	0.882	0.69	0.773	0.555

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	C/EBP-related {1.1.8} (TFClass)
TF subfamily	PAR {1.1.8.2} (TFClass)
TFClass ID	TFClass: 1.1.8.2.2
HGNC	HGNC:4977
MGI	MGI:96108
EntrezGene (human)	GeneID:3131 (SSTAR profile)
EntrezGene (mouse)	GeneID:217082 (SSTAR profile)
UniProt ID (human)	HLF_HUMAN
UniProt ID (mouse)	HLF_MOUSE
UniProt AC (human)	Q16534 (TFClass)
UniProt AC (mouse)	Q8BW74 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 3 mouse
HT-SELEX	5
Methyl-HT-SELEX	1

PCM	HLF.H12INVIVO.0.P.B.pcm
PWM	HLF.H12INVIVO.0.P.B.pwm
PFM	HLF.H12INVIVO.0.P.B.pfm
Alignment	HLF.H12INVIVO.0.P.B.words.tsv
Threshold to P-value map	HLF.H12INVIVO.0.P.B.thr
Motif in other formats
JASPAR format	HLF.H12INVIVO.0.P.B_jaspar_format.txt
MEME format	HLF.H12INVIVO.0.P.B_meme_format.meme
Transfac format	HLF.H12INVIVO.0.P.B_transfac_format.txt
Homer format	HLF.H12INVIVO.0.P.B_homer_format_0.001.txt HLF.H12INVIVO.0.P.B_homer_format_0.0005.txt HLF.H12INVIVO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	223.0	195.0	550.0	18.0
02	0.0	2.0	1.0	983.0
03	0.0	0.0	41.0	945.0
04	944.0	0.0	42.0	0.0
05	1.0	282.0	1.0	702.0
06	324.0	3.0	654.0	5.0
07	0.0	865.0	3.0	118.0
08	976.0	10.0	0.0	0.0
09	983.0	0.0	3.0	0.0
10	25.0	553.0	167.0	241.0

PFM

	A	C	G	T
01	0.226	0.198	0.558	0.018
02	0.0	0.002	0.001	0.997
03	0.0	0.0	0.042	0.958
04	0.957	0.0	0.043	0.0
05	0.001	0.286	0.001	0.712
06	0.329	0.003	0.663	0.005
07	0.0	0.877	0.003	0.12
08	0.99	0.01	0.0	0.0
09	0.997	0.0	0.003	0.0
10	0.025	0.561	0.169	0.244

PWM

	A	C	G	T
01	-0.099	-0.233	0.799	-2.533
02	-4.97	-4.2	-4.512	1.378
03	-4.97	-4.97	-1.76	1.339
04	1.338	-4.97	-1.736	-4.97
05	-4.512	0.134	-4.512	1.042
06	0.272	-3.962	0.971	-3.609
07	-4.97	1.25	-3.962	-0.729
08	1.371	-3.053	-4.97	-4.97
09	1.378	-4.97	-3.962	-4.97
10	-2.229	0.804	-0.386	-0.022

Standard thresholds

P-value	Threshold
0.001	2.63188
0.0005	3.983635
0.0001	6.83981