HLF.H12CORE.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	HLF.H12CORE.0.P.B
Gene (human)	HLF (GeneCards)
Gene synonyms (human)
Gene (mouse)	Hlf
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	11
Consensus	vTTATGYAAYh
GC content	32.25%
Information content (bits; total / per base)	13.339 / 1.213
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.982	0.984	0.964	0.966	0.978	0.98	5.036	5.084	1031.137	1066.284
Mouse	3 (16)	0.917	0.95	0.85	0.884	0.901	0.933	3.483	3.757	400.45	463.509

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.839	0.824	0.677	0.688	0.583	0.609
Overall, 6 experiments	best	0.986	0.975	0.981	0.968	0.96	0.943
Methyl HT-SELEX, 1 experiments	median	0.986	0.975	0.981	0.968	0.96	0.943
Methyl HT-SELEX, 1 experiments	best	0.986	0.975	0.981	0.968	0.96	0.943
Non-Methyl HT-SELEX, 5 experiments	median	0.761	0.758	0.625	0.639	0.562	0.581
Non-Methyl HT-SELEX, 5 experiments	best	0.982	0.968	0.975	0.958	0.947	0.927

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	10.07	5.034	0.246	0.202

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.854	0.307	0.87	0.515
batch 2	0.858	0.703	0.806	0.594

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	C/EBP-related {1.1.8} (TFClass)
TF subfamily	PAR {1.1.8.2} (TFClass)
TFClass ID	TFClass: 1.1.8.2.2
HGNC	HGNC:4977
MGI	MGI:96108
EntrezGene (human)	GeneID:3131 (SSTAR profile)
EntrezGene (mouse)	GeneID:217082 (SSTAR profile)
UniProt ID (human)	HLF_HUMAN
UniProt ID (mouse)	HLF_MOUSE
UniProt AC (human)	Q16534 (TFClass)
UniProt AC (mouse)	Q8BW74 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 3 mouse
HT-SELEX	5
Methyl-HT-SELEX	1

PCM	HLF.H12CORE.0.P.B.pcm
PWM	HLF.H12CORE.0.P.B.pwm
PFM	HLF.H12CORE.0.P.B.pfm
Alignment	HLF.H12CORE.0.P.B.words.tsv
Threshold to P-value map	HLF.H12CORE.0.P.B.thr
Motif in other formats
JASPAR format	HLF.H12CORE.0.P.B_jaspar_format.txt
MEME format	HLF.H12CORE.0.P.B_meme_format.meme
Transfac format	HLF.H12CORE.0.P.B_transfac_format.txt
Homer format	HLF.H12CORE.0.P.B_homer_format_0.001.txt HLF.H12CORE.0.P.B_homer_format_0.0005.txt HLF.H12CORE.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	236.0	199.0	512.0	53.0
02	1.0	0.0	0.0	999.0
03	0.0	0.0	79.0	921.0
04	796.0	2.0	195.0	7.0
05	6.0	60.0	21.0	913.0
06	126.0	3.0	864.0	7.0
07	13.0	426.0	2.0	559.0
08	989.0	10.0	1.0	0.0
09	996.0	0.0	4.0	0.0
10	25.0	571.0	170.0	234.0
11	345.0	322.0	107.0	226.0

PFM

	A	C	G	T
01	0.236	0.199	0.512	0.053
02	0.001	0.0	0.0	0.999
03	0.0	0.0	0.079	0.921
04	0.796	0.002	0.195	0.007
05	0.006	0.06	0.021	0.913
06	0.126	0.003	0.864	0.007
07	0.013	0.426	0.002	0.559
08	0.989	0.01	0.001	0.0
09	0.996	0.0	0.004	0.0
10	0.025	0.571	0.17	0.234
11	0.345	0.322	0.107	0.226

PWM

	A	C	G	T
01	-0.057	-0.226	0.713	-1.526
02	-4.525	-4.982	-4.982	1.38
03	-4.982	-4.982	-1.137	1.299
04	1.153	-4.213	-0.247	-3.362
05	-3.484	-1.406	-2.405	1.29
06	-0.678	-3.975	1.235	-3.362
07	-2.839	0.53	-4.213	0.801
08	1.37	-3.066	-4.525	-4.982
09	1.377	-4.982	-3.783	-4.982
10	-2.243	0.822	-0.382	-0.066
11	0.32	0.252	-0.84	-0.1

Standard thresholds

P-value	Threshold
0.001	3.18528
0.0005	4.450525
0.0001	7.0767