HINFP.H12INVITRO.2.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	HINFP.H12INVITRO.2.S.B
Gene (human)	HINFP (GeneCards)
Gene synonyms (human)	MIZF, ZNF743
Gene (mouse)	Hinfp
Gene synonyms (mouse)	Mizf
LOGO
LOGO (reverse complement)
Motif subtype	2
Quality	B

Motif length	12
Consensus	nhGCGGACSbnn
GC content	70.09%
Information content (bits; total / per base)	12.407 / 1.034
Data sources	HT-SELEX
Aligned words	767

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	4 (25)	0.66	0.753	0.546	0.602	0.551	0.71	1.559	2.093	21.066	118.108

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.62	0.644	0.534	0.564	0.505	0.531
Non-Methyl HT-SELEX, 2 experiments	best	0.671	0.697	0.552	0.589	0.512	0.545

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Multiple dispersed zinc fingers {2.3.4} (TFClass)
TF subfamily	HINFP-like {2.3.4.21} (TFClass)
TFClass ID	TFClass: 2.3.4.21.1
HGNC	HGNC:17850
MGI	MGI:2429620
EntrezGene (human)	GeneID:25988 (SSTAR profile)
EntrezGene (mouse)	GeneID:102423 (SSTAR profile)
UniProt ID (human)	HINFP_HUMAN
UniProt ID (mouse)	HINFP_MOUSE
UniProt AC (human)	Q9BQA5 (TFClass)
UniProt AC (mouse)	Q8K1K9 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	4 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	HINFP.H12INVITRO.2.S.B.pcm
PWM	HINFP.H12INVITRO.2.S.B.pwm
PFM	HINFP.H12INVITRO.2.S.B.pfm
Alignment	HINFP.H12INVITRO.2.S.B.words.tsv
Threshold to P-value map	HINFP.H12INVITRO.2.S.B.thr
Motif in other formats
JASPAR format	HINFP.H12INVITRO.2.S.B_jaspar_format.txt
MEME format	HINFP.H12INVITRO.2.S.B_meme_format.meme
Transfac format	HINFP.H12INVITRO.2.S.B_transfac_format.txt
Homer format	HINFP.H12INVITRO.2.S.B_homer_format_0.001.txt HINFP.H12INVITRO.2.S.B_homer_format_0.0005.txt HINFP.H12INVITRO.2.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	211.25	225.25	172.25	158.25
02	175.25	362.25	95.25	134.25
03	53.0	2.0	707.0	5.0
04	0.0	765.0	0.0	2.0
05	0.0	0.0	767.0	0.0
06	0.0	0.0	767.0	0.0
07	767.0	0.0	0.0	0.0
08	4.0	755.0	4.0	4.0
09	42.0	205.0	459.0	61.0
10	87.0	248.0	109.0	323.0
11	172.75	126.75	216.75	250.75
12	176.0	196.0	269.0	126.0

PFM

	A	C	G	T
01	0.275	0.294	0.225	0.206
02	0.228	0.472	0.124	0.175
03	0.069	0.003	0.922	0.007
04	0.0	0.997	0.0	0.003
05	0.0	0.0	1.0	0.0
06	0.0	0.0	1.0	0.0
07	1.0	0.0	0.0	0.0
08	0.005	0.984	0.005	0.005
09	0.055	0.267	0.598	0.08
10	0.113	0.323	0.142	0.421
11	0.225	0.165	0.283	0.327
12	0.229	0.256	0.351	0.164

PWM

	A	C	G	T
01	0.096	0.16	-0.106	-0.19
02	-0.089	0.632	-0.691	-0.353
03	-1.264	-3.967	1.299	-3.369
04	-4.758	1.377	-4.758	-3.967
05	-4.758	-4.758	1.38	-4.758
06	-4.758	-4.758	1.38	-4.758
07	1.38	-4.758	-4.758	-4.758
08	-3.531	1.364	-3.531	-3.531
09	-1.488	0.066	0.868	-1.127
10	-0.78	0.255	-0.558	0.518
11	-0.103	-0.41	0.122	0.266
12	-0.085	0.022	0.336	-0.415

Standard thresholds

P-value	Threshold
0.001	3.306965
0.0005	4.395225
0.0001	7.73498