| Motif | HIF1A.H12RSNP.0.P.B |
| Gene (human) | HIF1A (GeneCards) |
| Gene synonyms (human) | BHLHE78, MOP1, PASD8 |
| Gene (mouse) | Hif1a |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | HIF1A.H12RSNP.0.P.B |
| Gene (human) | HIF1A (GeneCards) |
| Gene synonyms (human) | BHLHE78, MOP1, PASD8 |
| Gene (mouse) | Hif1a |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 8 |
| Consensus | vKACGTGM |
| GC content | 60.2% |
| Information content (bits; total / per base) | 9.665 / 1.208 |
| Data sources | ChIP-Seq |
| Aligned words | 999 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 24 (137) | 0.834 | 0.924 | 0.764 | 0.89 | 0.8 | 0.909 | 2.666 | 3.516 | 169.0 | 425.432 |
| Mouse | 4 (25) | 0.839 | 0.882 | 0.743 | 0.801 | 0.828 | 0.881 | 2.771 | 3.377 | 176.796 | 291.292 |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 18.972 | 11.551 | 0.291 | 0.184 |
| TF superclass | Basic domains {1} (TFClass) |
| TF class | Basic helix-loop-helix factors (bHLH) {1.2} (TFClass) |
| TF family | PAS {1.2.5} (TFClass) |
| TF subfamily | PAS-AHR {1.2.5.1} (TFClass) |
| TFClass ID | TFClass: 1.2.5.1.5 |
| HGNC | HGNC:4910 |
| MGI | MGI:106918 |
| EntrezGene (human) | GeneID:3091 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:15251 (SSTAR profile) |
| UniProt ID (human) | HIF1A_HUMAN |
| UniProt ID (mouse) | HIF1A_MOUSE |
| UniProt AC (human) | Q16665 (TFClass) |
| UniProt AC (mouse) | Q61221 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 24 human, 4 mouse |
| HT-SELEX | 0 |
| Methyl-HT-SELEX | 0 |
| PCM | HIF1A.H12RSNP.0.P.B.pcm |
| PWM | HIF1A.H12RSNP.0.P.B.pwm |
| PFM | HIF1A.H12RSNP.0.P.B.pfm |
| Alignment | HIF1A.H12RSNP.0.P.B.words.tsv |
| Threshold to P-value map | HIF1A.H12RSNP.0.P.B.thr |
| Motif in other formats | |
| JASPAR format | HIF1A.H12RSNP.0.P.B_jaspar_format.txt |
| MEME format | HIF1A.H12RSNP.0.P.B_meme_format.meme |
| Transfac format | HIF1A.H12RSNP.0.P.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 161.0 | 240.0 | 503.0 | 95.0 |
| 02 | 115.0 | 11.0 | 390.0 | 483.0 |
| 03 | 808.0 | 4.0 | 176.0 | 11.0 |
| 04 | 61.0 | 916.0 | 7.0 | 15.0 |
| 05 | 28.0 | 2.0 | 967.0 | 2.0 |
| 06 | 1.0 | 3.0 | 0.0 | 995.0 |
| 07 | 1.0 | 0.0 | 998.0 | 0.0 |
| 08 | 320.0 | 534.0 | 60.0 | 85.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.161 | 0.24 | 0.504 | 0.095 |
| 02 | 0.115 | 0.011 | 0.39 | 0.483 |
| 03 | 0.809 | 0.004 | 0.176 | 0.011 |
| 04 | 0.061 | 0.917 | 0.007 | 0.015 |
| 05 | 0.028 | 0.002 | 0.968 | 0.002 |
| 06 | 0.001 | 0.003 | 0.0 | 0.996 |
| 07 | 0.001 | 0.0 | 0.999 | 0.0 |
| 08 | 0.32 | 0.535 | 0.06 | 0.085 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.435 | -0.04 | 0.697 | -0.955 |
| 02 | -0.768 | -2.984 | 0.443 | 0.656 |
| 03 | 1.169 | -3.782 | -0.347 | -2.984 |
| 04 | -1.389 | 1.295 | -3.361 | -2.71 |
| 05 | -2.135 | -4.212 | 1.349 | -4.212 |
| 06 | -4.524 | -3.974 | -4.981 | 1.377 |
| 07 | -4.524 | -4.981 | 1.38 | -4.981 |
| 08 | 0.246 | 0.756 | -1.405 | -1.065 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.004325 |
| 0.0005 | 6.004635 |
| 0.0001 | 7.505245 |