MotifHIF1A.H12INVIVO.1.P.B
Gene (human)HIF1A
(GeneCards)
Gene synonyms (human)BHLHE78, MOP1, PASD8
Gene (mouse)Hif1a
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length19
ConsensusvdACGTGMbnnnnnnSvbv
GC content58.33%
Information content (bits; total / per base)10.903 / 0.574
Data sourcesChIP-Seq
Aligned words1000

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 24 (137) 0.843 0.932 0.785 0.891 0.818 0.931 3.324 4.426 177.796 467.292
Mouse 4 (25) 0.826 0.876 0.736 0.807 0.819 0.869 3.014 3.76 167.509 275.538

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 12.878 9.734 0.287 0.17
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familyPAS {1.2.5} (TFClass)
TF subfamilyPAS-AHR {1.2.5.1} (TFClass)
TFClass IDTFClass: 1.2.5.1.5
HGNCHGNC:4910
MGIMGI:106918
EntrezGene (human)GeneID:3091
(SSTAR profile)
EntrezGene (mouse)GeneID:15251
(SSTAR profile)
UniProt ID (human)HIF1A_HUMAN
UniProt ID (mouse)HIF1A_MOUSE
UniProt AC (human)Q16665
(TFClass)
UniProt AC (mouse)Q61221
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 24 human, 4 mouse
HT-SELEX 0
Methyl-HT-SELEX 0
PCM
ACGT
01158.0278.0490.074.0
02144.0104.0237.0515.0
03856.013.0129.02.0
044.0939.021.036.0
0532.030.0934.04.0
062.01.02.0995.0
070.00.0998.02.0
08272.0589.043.096.0
09178.0404.0203.0215.0
10175.0243.0228.0354.0
11248.0185.0374.0193.0
12228.0257.0255.0260.0
13218.0287.0280.0215.0
14240.0223.0320.0217.0
15177.0194.0369.0260.0
16103.0638.0182.077.0
17539.0162.0190.0109.0
18136.0384.0253.0227.0
19244.0156.0488.0112.0
PFM
ACGT
010.1580.2780.490.074
020.1440.1040.2370.515
030.8560.0130.1290.002
040.0040.9390.0210.036
050.0320.030.9340.004
060.0020.0010.0020.995
070.00.00.9980.002
080.2720.5890.0430.096
090.1780.4040.2030.215
100.1750.2430.2280.354
110.2480.1850.3740.193
120.2280.2570.2550.26
130.2180.2870.280.215
140.240.2230.320.217
150.1770.1940.3690.26
160.1030.6380.1820.077
170.5390.1620.190.109
180.1360.3840.2530.227
190.2440.1560.4880.112
PWM
ACGT
01-0.4550.1050.67-1.201
02-0.547-0.867-0.0530.719
031.226-2.839-0.655-4.213
04-3.7831.318-2.405-1.898
05-2.01-2.0711.313-3.783
06-4.213-4.525-4.2131.376
07-4.982-4.9821.379-4.213
080.0840.853-1.728-0.946
09-0.3370.477-0.207-0.15
10-0.354-0.028-0.0910.346
11-0.008-0.2990.401-0.257
12-0.0910.0270.020.039
13-0.1360.1370.113-0.15
14-0.041-0.1130.245-0.141
15-0.342-0.2520.3870.039
16-0.8770.933-0.315-1.162
170.765-0.43-0.272-0.821
18-0.6030.4270.012-0.096
19-0.024-0.4670.666-0.795
Standard thresholds
P-value Threshold
0.001 4.55656
0.0005 5.54311
0.0001 7.40831