MotifHIF1A.H12INVIVO.0.P.B
Gene (human)HIF1A
(GeneCards)
Gene synonyms (human)BHLHE78, MOP1, PASD8
Gene (mouse)Hif1a
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length11
ConsensusbbvKACGTGMh
GC content58.84%
Information content (bits; total / per base)10.592 / 0.963
Data sourcesChIP-Seq
Aligned words218

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 24 (137) 0.847 0.935 0.781 0.899 0.808 0.925 2.9 4.014 178.347 450.444
Mouse 4 (25) 0.85 0.888 0.75 0.798 0.831 0.884 2.803 3.314 196.022 313.585

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 18.972 11.551 0.279 0.173
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familyPAS {1.2.5} (TFClass)
TF subfamilyPAS-AHR {1.2.5.1} (TFClass)
TFClass IDTFClass: 1.2.5.1.5
HGNCHGNC:4910
MGIMGI:106918
EntrezGene (human)GeneID:3091
(SSTAR profile)
EntrezGene (mouse)GeneID:15251
(SSTAR profile)
UniProt ID (human)HIF1A_HUMAN
UniProt ID (mouse)HIF1A_MOUSE
UniProt AC (human)Q16665
(TFClass)
UniProt AC (mouse)Q61221
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 24 human, 4 mouse
HT-SELEX 0
Methyl-HT-SELEX 0
PCM
ACGT
0124.030.0107.057.0
0240.045.089.044.0
0354.051.0102.011.0
0435.09.055.0119.0
05189.05.019.05.0
060.0212.01.05.0
073.00.0214.01.0
080.00.00.0218.0
090.00.0218.00.0
1082.0103.010.023.0
1143.0112.029.034.0
PFM
ACGT
010.110.1380.4910.261
020.1830.2060.4080.202
030.2480.2340.4680.05
040.1610.0410.2520.546
050.8670.0230.0870.023
060.00.9720.0050.023
070.0140.00.9820.005
080.00.00.01.0
090.00.01.00.0
100.3760.4720.0460.106
110.1970.5140.1330.156
PWM
ACGT
01-0.79-0.5780.6630.044
02-0.301-0.1860.481-0.208
03-0.009-0.0650.615-1.509
04-0.43-1.6860.0090.768
051.226-2.175-1.01-2.175
06-3.7251.34-3.17-2.175
07-2.553-3.7251.35-3.17
08-3.725-3.725-3.7251.368
09-3.725-3.7251.368-3.725
100.40.625-1.594-0.83
11-0.2310.708-0.61-0.457
Standard thresholds
P-value Threshold
0.001 4.71862
0.0005 5.71494
0.0001 7.56948